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Now showing items 662-681 of 1185
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Minimising Young Children’s Anxiety through Schools (MY-CATS): Protocol for a Cluster Randomised Controlled Trial to Evaluate the Effectiveness and Cost-effectiveness of an Online Parent-led Intervention Compared With Usual School Practice for Young Children Identified as atrisk for Anxiety Disorders
(2022-01)Identifying and supporting young children who are at-risk of developing anxiety disorders would benefit children, families, and wider society. Elevated anxiety symptoms, inhibited temperament, and high parental anxiety ... -
Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease A Randomized Clinical Trial
(2019-11)IMPORTANCE There are no disease-modifying treatments for Alzheimer disease (AD), the most common cause of dementia. Minocycline is anti-inflammatory, protects against the toxic effects of β-amyloid in vitro and in animal ... -
Misophonia in the UK: norms of the selective sound sensitivity five factor model (S-Five) for misophonia and prevalence of the disorder using a large sample representative of the UK population
(2022-04)What is the reality of the misophonic experience in the general population? This is a study on misophonia in a large sample, representative of the UK general population. The study utilises a multidimensional psychometric ... -
Misophonia in the UK: Prevalence and norms from the S-Five in a UK representative sample
(2023-03)What is the reality of the misophonic experience in the general population? This is a study on misophonia in a large sample, representative of the UK general population. The study utilises a multidimensional psychometric ... -
Mixed effects approach to the analysis of the stepped wedge cluster randomised trial—Investigating the confounding effect of time through simulation
(2018-12)A stepped wedge cluster randomised trial (SWCRT) is a multicentred study which allows an intervention to be rolled out at sites in a random order. Once the intervention is initiated at a site, all participants within that ... -
Mixed methods case study exploring primary care antibiotic prescribing practices and maternal expectations of using antibiotics in children
(2021-10)Overuse of antibiotics and inappropriate prescribing has resulted in rapid development of antimicrobial resistance. Most antibiotics in the United Kingdom (71.4%) are prescribed in primary care by general practitioners, ... -
Modelling paralinguistic properties in conversational speech to detect bipolar disorder and borderline personality disorder
(2021-02)Bipolar disorder (BD) and borderline personality disorder (BPD) are two chronic mental health conditions that clinicians find challenging to distinguish based on clinical interviews, due to their overlapping symptoms. In ... -
Modelling suicide in bipolar disorders: Limitations and opportunities
(2018-07)Commentary on: Malhi GS, Outhred T, Das P et al. Modeling suicide in bipolar disorders. Bipolar Disord. 2018. In their paper in this issue, Malhi et al highlight a key clinical area; whilst suicide rates are increased in ... -
Moderators and mediators of outcome in treatments for anorexia nervosa and bulimia nervosa in adolescents: A systematic review of randomized controlled trials
(2019-09)Objective:To critically appraise papers reporting on moderators and mediators of recommended psychological treatments for anorexia nervosa (AN) and bulimia nervosa (BN) in adolescents. Method:A systematic search of databases ... -
Modifiable risk factors for inpatient violence in psychiatric hospital: prospective study and prediction model
(2021-05)Background. Violence perpetrated by psychiatric inpatients is associated with modifiable factors. Current structured approaches to assess inpatient violence risk lack predictive validity and linkage to interventions. Methods. ... -
Modulation of the pupillary response by the content of visual working memory
(2019-09)Studies of selective attention during perception have revealed modulation of the pupillary response according to the brightness of task-relevant (attended) vs. -irrelevant (unattended) stimuli within a visual display. ... -
Molecular and antibody point-of-care tests to support the screening, diagnosis and monitoring of COVID-19
(2020-04)Moving diagnostic testing for COVID-19 from laboratory settings to the point of care is potentially transformative in the rate and quantity of testing that could be performed. Eleven diagnostic tests that are potentially ... -
Mood Homeostasis, Low Mood, and History of Depression in 2 Large Population Samples
(2020-04)Importance Existing therapeutic options are insufficient to tackle the disease burden of depression, and new treatments are sorely needed. Defining new psychotherapeutic targets is challenging given the paucity of coherent ... -
Mortality in children and adolescents who present to hospital following non-fatal self-harm: an observational cohort study based on the Multicentre Study of Self-harm in England
(2020-02)Background Self-harm and suicide in children and adolescents are both growing problems, with self-harm associated with a significant risk of subsequent death, particularly suicide. Long-term follow-up studies are necessary ... -
Mortality in psychotic depression: 18-year follow-up study
(2022-10)Background Evidence on the role of co-occurring psychiatric disorders in mortality associated with psychotic depression is limited. Aims To estimate the risk of cause-specific mortality in psychotic depression compared ... -
Mothers’ accounts of the impact of being in nature on postnatal wellbeing: a focus group study
(2023-06)Background The postnatal period is a vulnerable time for mothers to experience stress and mental health difculties. There is increasing evidence that spending time in nature is benefcial for wellbeing. Nature-based ... -
Mothers’ accounts of the impact of being in nature on postnatal wellbeing: a focus group study
(2023-01)The postnatal period is a vulnerable time for mothers to experience stress and mental health difficulties. There is increasing evidence that spending time in nature is beneficial for wellbeing. Nature-based interventions ... -
Motivational Interviewing-based interventions for reducing substance misuse and increasing treatment engagement, retention, and completion in the homeless populations of high-income countries: An equity-focused systematic review and narrative synthesis
(2021-11)Rising mortality and disease prevalence in the homeless have been largely attributed to addiction disorders. This review aimed to assess whether Motivational Interviewing (MI) is effective in changing substance misuse ... -
Multi-scale neural signatures of major depressive, anxiety, and stress-related disorders
(2021-07)The extent of shared and distinct neural mechanisms underlying major depressive disorder (MDD), anxiety and stress-related disorders is still unclear. We compared the neural signatures of these disorders in 5,405 UK Biobank ... -
Multidisciplinary Teamwork and the Insanity Defence: A Case of Infanticide in Iraq
(2020-12)Capital punishment still exists in many countries and mainly in the Middle East where Islam is the main formal religion for most states. Here, the author describes the case of a young woman from Iraq who was arrested by ...