Browsing by Title
Now showing items 148-167 of 249
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Observational analysis of disparities in obesity in children in the UK: Has Leeds bucked the trend?
(2019-03)Background: The prevalence of obesity in childhood is of high concern, especially in deprived populations. We explored trends in obesity following the introduction of a citywide strategy focused on preschool children. Methods: ... -
One step closer to personalised prescribing of antidepressants: using real-world data together with patients and clinicians' preferences
(2019-07)Antidepressants for many decades have been shown to be an effective treatment for depressive disorder.1 Approximately 80% of people with depressive disorder in the UK will have been prescribed an antidepressant within the ... -
An online survey of young adolescent girls’ use of the internet and smartphone apps for mental health support
(2018-07)Background Adolescents are digital natives, with the majority now owning their own smartphones and having internet access. Although the internet and smartphone applications (apps) can provide mental health support, little ... -
Out-of-area placements in acute mental health care: the outcomes
(2019-02)Out-of-area placements (OAPs) are heavily relied upon by the NHS to meet growing demand but they are expensive, disruptive for patients, and may reduce quality of care and outcomes for patients. Here, the authors compared ... -
Out-of-hours primary care end of life prescribing: a data linkage study
(2019-05)Objectives: Out-of-hours (OOH) primary care services are contacted in the last 4 weeks of life by nearly 30% of all patients who die, but OOH palliative prescribing remains poorly understood. Our understanding of prescribing ... -
The Oxford study of Calcium channel Antagonism, Cognition, Mood instability and Sleep (OxCaMS): study protocol for a randomised controlled, experimental medicine study
(2019-02)Background: The discovery that voltage-gated calcium channel genes such as CACNA1C are part of the aetiology of psychiatric disorders has rekindled interest in the therapeutic potential of L-type calcium channel (LTCC) ... -
The Oxford Textbook of Inpatient Psychiatry
(Oxford University Press, 2019-05)Inpatient mental health care is an essential part of community-based mental health care in the UK. Patients admitted to acute mental health wards are often experiencing high levels of distress and acute mental illness and ... -
Paediatric enteral feeding at home: an analysis of patient safety incidents
(2019-06)Aims To describe the nature and causes of patient safety incidents relating to care at home for children with enteral feeding devices. Methods We analysed incident data relating to paediatric nasogastric, gastrostomy ... -
A Parenting Programme for Muslims
(2018-03)Universal parenting intervention courses often fail to recruit and retain Muslim families. The practice of targeting specific populations in parenting programs is not well established. Parents from minority backgrounds are ... -
A Path Signature Approach for Speech Emotion Recognition
(2019-09)Automatic speech emotion recognition (SER) remains a difficult task within human-computer interaction, despite increasing interest in the research community. One key challenge is how to effectively integrate short-term ... -
Patient and public involvement in reducing health and care research waste
(2018-01-08)Background: Eighty five per cent of health research expenditure is potentially wasted due to failure to publish research, unclear reporting of research that is published, and the failure of new research studies to ... -
Patient experience of home and waiting room blood pressure measurement: a qualitative study of patients with recently diagnosed hypertension
(2018-12)Background Out-of-office blood pressure (BP) measurement is advocated to confirm hypertension diagnosis. However, little is known about how primary care patients view and use such measurement. Aim To investigate patient ... -
Patient safety regulation in the NHS: mapping the regulatory landscape of healthcare
(2019-07)Objectives The current research project sought to map out the regulatory landscape for patient safety in the English National Health Service (NHS). Method We used a systematic desk-based search using a variety of sources ... -
Plasma glutathione suggests oxidative stress is equally present in early- and late- onset bipolar disorder
(2018-03)We previously demonstrated oxidative stress in bipolar patients and a relationship between the age of illness onset and total glutathione, a principal antioxi- dant. In this study, we sought to replicate these findings ... -
Polyunsaturated fatty acids metabolism, purine metabolism and inosine as potential independent diagnostic biomarkers for major depressive disorder in children and adolescents
(2018-04-20)Major depressive disorder (MDD) in children and adolescents is a recurrent and disabling condition globally but its pathophysiology remains poorly elucidated and there are limited effective treatments available. We performed ... -
Potential Interventions for Preventing Pesticide Self-Poisoning by Restricting Access Through Vendors in Sri Lanka: A Study of Stakeholders' Views
(2018-06)Background: In South Asia, up to one in five individuals who use pesticides for self-harm purchase them immediately prior to the event. Aims: From reviewing the literature we proposed four interventions: (a) farmer ... -
Predicting clinical deterioration after initial assessment in out-of-hours primary care: a retrospective service evaluation
(2017-01)Background: Accurate assessment of the need for admission is challenging in out-of-hours (OOH) primary care. Understanding more about patient contacts where the decision to continue care in the community may have been ... -
Predicting treatment response in depression: the role of anterior cingulate cortex
(2018)Background: Identification of biomarkers predicting therapeutic outcome to antidepressant treatment is one of the most important tasks in current research because it may transform the lengthy process of finding the right ... -
Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis
(2018-01-30)Preclinical models propose that the onset of psychosis is associated with hippocampal hyperactivity, thought to be driven by cortical GABAergic interneuron dysfunction and disinhibition of pyramidal neurons. Recent ... -
Preparing the workforce for frailty, an education intervention for allied health professionals and community nurses in primary and community healthcare
(2019-01)The Comprehensive Geriatric Assessment (CGA) is a multidisciplinary assessment that identifies the medical, psychosocial, and functional needs of older people. This service evaluation considers the impact of training allied ...
