Browsing by Title
Now showing items 372-391 of 591
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Paediatric contacts with the UK out-of-hours primary care service and contact outcomes: a regional service evaluation
(2020-07)Background Demand on hospital emergency departments for paediatric problems is increasing. However, the volume and nature of paediatric health demands placed on other parts of the urgent care system have not been explored. ... -
Paediatric enteral feeding at home: an analysis of patient safety incidents
(2019-06)Aims To describe the nature and causes of patient safety incidents relating to care at home for children with enteral feeding devices. Methods We analysed incident data relating to paediatric nasogastric, gastrostomy ... -
Parenting behaviour and paranoia: a network analysis and results from the National Comorbidity Survey-Adolescents (NCS-A)
(2020-08)Method We examined cross-sectional associations of parenting and paranoia in an epidemiologically representative cohort of 10,148 adolescents (National Comorbidity Survey-Adolescents; NCS-A) and a second dataset of 1286 ... -
Parenting behaviour and paranoia: a network analysis and results from the National Comorbidity Survey‑Adolescents (NCS‑A)
(2020-08)Parenting behaviours—including the extent to which parents are protective, hostile, or caring—likely impacts whether a child develops a sense of vulnerability that carries forward into adulthood. Ideas of vulnerability are ... -
A Parenting Programme for Muslims
(2018-03)Universal parenting intervention courses often fail to recruit and retain Muslim families. The practice of targeting specific populations in parenting programs is not well established. Parents from minority backgrounds are ... -
A Path Signature Approach for Speech Emotion Recognition
(2019-09)Automatic speech emotion recognition (SER) remains a difficult task within human-computer interaction, despite increasing interest in the research community. One key challenge is how to effectively integrate short-term ... -
Patient and public involvement in reducing health and care research waste
(2018-01-08)Background: Eighty five per cent of health research expenditure is potentially wasted due to failure to publish research, unclear reporting of research that is published, and the failure of new research studies to ... -
Patient experience of home and waiting room blood pressure measurement: a qualitative study of patients with recently diagnosed hypertension
(2018-12)Background Out-of-office blood pressure (BP) measurement is advocated to confirm hypertension diagnosis. However, little is known about how primary care patients view and use such measurement. Aim To investigate patient ... -
Patient fibroblast circadian rhythms predict lithium sensitivity in bipolar disorder
(2020-05)Bipolar disorder is a chronic neuropsychiatric condition associated with mood instability, where patients present significant sleep and circadian rhythm abnormalities. Currently, the pathophysiology of bipolar disorder ... -
Patient safety regulation in the NHS: mapping the regulatory landscape of healthcare
(2019-07)Objectives The current research project sought to map out the regulatory landscape for patient safety in the English National Health Service (NHS). Method We used a systematic desk-based search using a variety of sources ... -
Patterns in Weight and Physical Activity Tracking Data Preceding a Stop in Weight Monitoring: Observational Analysis
(2020-03)Background: Self-regulation for weight loss requires regular self-monitoring of weight, but the frequency of weight tracking commonly declines over time. Objective: This study aimed to investigate whether it is a decline ... -
Patterns in Weight and Physical Activity Tracking Data Preceding a Stop in Weight Monitoring: Observational Analysis
(2020-03)Background: Self-regulation for weight loss requires regular self-monitoring of weight, but the frequency of weight tracking commonly declines over time. Objective: This study aimed to investigate whether it is a decline ... -
Perceptions and experiences of employee mental health support: a cross-sectional survey of UK ambulance service staff
(2020-09)Background Mental ill health among ambulance staff is widespread. Evidence suggests that, with the right support, staff experiencing mental ill health can continue to work, symptom severity can be reduced and suicide ... -
Personalise antidepressant treatment for unipolar depression combining individual choices, risks and big data (PETRUSHKA): rationale and protocol
(2019-10)Introduction: Matching treatment to specific patients is too often a matter of trial and error, while treatment efficacy should be optimised by limiting risks and costs and by incorporating patients’ preferences. Factors ... -
Pharmaceutical industry, academia and people with experience of mental illness as partners in research: a need for ethical guidance [version 1; peer review: 1 not approved]
(2020-08)Background: Several social and policy developments have led to research partnerships in mental health research, which depart from traditional research models. One form of such partnerships is among research institutions, ... -
Pharmacological Augmentation in Unipolar Depression: A Guide to the Guidelines
(2020-05)Background: Pharmacological augmentation is a recommended strategy for patients with treatment-resistant depression. A range of guidelines provide advice on treatment selection, prescription, monitoring and discontinuation, ... -
Pharmacological interventions for self-harm in adults (Protocol)
(2020-07)This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the effects of psychosocial or pharmacological interventions for self‐harm (SH) compared to comparison types of care (e.g. ... -
Pharmacological Treatments for Social Anxiety Disorder in Adults: A Systematic Review and Network Meta-Analysis
(2020-02)Objective: The aim of this paper was to provide a systematic review and update on the pharmacotherapy of social anxiety disorder (SAD), including the efficacy and tolerability of these agents, the ranking of interventions, ... -
Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses
(2020-12)More than 190 vaccines are currently in development to prevent infection by the novel severe acute respiratory syndrome coronavirus 2. Animal studies suggest that while neutralizing antibodies against the viral spike protein ... -
A phase 2a randomised, double-blind, placebo-controlled, parallel-group, add-on clinical trial of ebselen (SPI-1005) as a novel treatment for mania or hypomania.
(2020-09)Rationale Lithium is an effective prophylactic and anti-manic treatment in bipolar disorder; however, its use is declining through perceived poor tolerance and toxicity. Lithium inhibits inositol monophosphatase (IMPase), ...
