Browsing by Title
Now showing items 22-41 of 249
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Barriers and facilitators of loaded self-managed exercises and physical activity in people with patellofemoral pain: understanding the feasibility of delivering a multicentred randomised controlled trial, a UK qualitative study
(2019-05)Objectives: There is an emergent body of evidence supporting exercise therapy and physical activity in the management of musculoskeletal pain. The purpose of this study was to explore potential barriers and facilitators ... -
Barriers and facilitators to implementing dementia care mapping in care homes: results from the DCM™ EPIC trial process evaluation
(2019-02)Background: Psychosocial person-centred interventions are considered best practice for addressing complex behaviours and care needs such as agitation and anxiety, and for improving the quality of life of people with ... -
Barriers and incentives to recruitment in mental health clinical trials
(2019-05)Research provides valuable information that improves patients’ outcomes and should inform clinical decision-making.1 There are many research methodologies2 and randomised controlled trials (RCTs) are at the top of the ... -
Best Methods of Communicating Clinical Trial Data to Improve Understanding of Treatments for Patients with Multiple Sclerosis
(2018-07)Background Patients’ understanding of treatment risks and benefits is a prerequisite for shared decision making. Yet, patients with multiple sclerosis (MS) do not accurately understand treatment information provided in ... -
Better Outcomes for Older people with Spinal Trouble (BOOST) Trial: a randomised controlled trial of a combined physical and psychological intervention for older adults with neurogenic claudication, a protocol
(2018-11)Introduction: Neurogenic claudication due to spinal stenosis is common in older adults. The effectiveness of conservative interventions is not known. The aim of the study is to estimate the clinical and cost-effectiveness ... -
Can rapid approaches to qualitative analysis deliver timely, valid findings to clinical leaders? A mixed methods study comparing rapid and thematic analysis
(2018-08)Objectives: This study compares rapid and traditional analyses of a UK health service evaluation dataset to explore differences in researcher time and consistency of outputs. Design: Mixed methods study, quantitatively ... -
Can Your Phone Be Your Therapist? Young People’s Ethical Perspectives on the Use of Fully Automated Conversational Agents (Chatbots) in Mental Health Support
(2019-03)Over the last decade, there has been an explosion of digital interventions that aim to either supplement or replace face-to-face mental health services. More recently, a number of automated conversational agents have also ... -
Care needs of people with dementia in the peri-operative environment: A systematic review
(2018-11)The care of people with dementia within the hospital setting is challenging for healthcare professionals. Hospital design and services are not optimized for people with dementia, owing to the lack of preparation of healthcare ... -
A case series to examine whether people with learning disabilities can learn prerequisite skills for cognitive behavioural therapy
(2018-01-17)Although cognitive behavioural therapy (CBT) is recommended for the treatment of a number of mental disorders among the general population, the ability of individuals with learning disabilities (LD) to understand CBT ... -
Changes in brain Glx in depressed bipolar patients treated with lamotrigine: A proton MRS study
(2019-03)Background Lamotrigine is a useful treatment in bipolar depression but requires several weeks of dose titration before its clinical effects can be assessed. Animal experimental studies suggest that lamotrigine lowers ... -
Characteristics of patients expressing an interest in ketamine treatment: results of an online survey
(2018-04)Off-label ketamine treatment has shown acute antidepressant effects that offer hope for patients with therapy-resistant depression. However, its potential for integration into treatment algorithms is controversial, not ... -
Characteristics of people with pressure ulcers using one year's routinely collected data in a defined diverse community
(2019-09)Objective:To determine if meaningful patient characteristics pertaining to pressure ulcers (PU) can be derived from routinely collected community health data. Methods: A retrospective cohort analysis of records was carried ... -
Characterizing the Digital Health Citizen: Mixed-Methods Study Deriving a New Typology
(2019-03)Background: A key challenge for health systems harnessing digital tools and services is that of digital inclusion. Typically, digital inequalities are conceptualized in relation to unequal access or usage. However, these ... -
Childhood Maltreatment and Violent Outcomes: A Systematic Review and Meta-Analysis of Prospective Studies
(2018-08)The risk of violence following childhood maltreatment is uncertain. This meta-analytic review identified prospective studies that have examined this association. We systematically searched three electronic databases ... -
Chronic psychosocial stressors are associated with alterations in salience processing and corticostriatal connectivity.
(2018-12-17)Psychosocial stressors including childhood adversity, migration, and living in an urban environment, have been associated with several psychiatric disorders, including psychotic disorders. The neural and psychological ... -
Claire E. Sexton, Konstantina Sykara, Elissaios Karageorgiou, Jenny Zitser, Talita Rosa, Kristine Yaffe, Yue Leng. Connections Between Insomnia and Cognitive Aging. Neuroscience Bulletin pp 1–8 June 2019.
(2019-06)Insomnia is a common sleep disorder among older adults, and a risk factor for poor physical and mental health. However, the relationship between insomnia and cognitive health is not well understood. Here, we review ... -
Clients' experience of change: an exploration of the influence of reformulation tools in Cognitive Analytic Therapy
(2018-10-10)Case formulation is considered important in both the development of the therapeutic relationship and in starting the process of therapeutic change. Cognitive analytic therapy describes the developmental origins and maintenance ... -
Clinician barriers and facilitators to heart failure advance care plans: a systematic literature review and qualitative evidence synthesis
(2019-07)Background:Clinicians hesitate to engage with advance care planning (ACP) in heart failure. We aimed to identify the disease-specific barriers and facilitators for clinicians to engage with ACP. Methods: We searched ... -
Clinician-targeted interventions to improve advance care planning in heart failure: a systematic review and meta-analysis
(2019-05)Objective Advance care planning (ACP) is widely advocated to contribute to better outcomes for patients suffering from heart failure. But clinicians appear hesitant to engage with ACP. Our aim was to identify interventions ... -
Clozapine-induced pericarditis: an ethical dilemma
(2019-06)Clozapine is an atypical antipsychotic used most frequently in the management of treatment-resistant schizophrenia, where severely unwell patients have failed to respond to standard antipsychotic therapy. Clozapine is ...
