Browsing by Title
Now showing items 128-147 of 591
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Defining the relationship between arm and leg blood pressure readings: a systematic review and meta-analysis
(2019-04)Objectives: To define the relationship between arm and leg blood pressure (BP) to inform the interpretation of leg BP readings in routine clinical practice where arm readings are not available. Methods: Systematic review ... -
Deprescribing antihypertensives in patients with multimorbidity
(2020-10)Deprescribing preventative medications such as antihypertensives may reduce adverse events in some older adults, leading to improved quality of life. The Optimising Treatment for Mild Systolic Hypertension in the ... -
Deriving information from missing data: implications for mood prediction
(2020-06)The availability of mobile technologies has enabled the efficient collection prospective longitudinal, ecologically valid self-reported mood data from psychiatric patients. These data streams have potential for improving ... -
Described practices for assessing fluid resuscitation in acute hospital care
(2019-09)Fluid resuscitation is a widely‐used treatment in acute and emergency medicine, however, the process used to perform a fluid assessment has never been studied. This qualitative study explored how acute physicians describe ... -
Developing a guided imagery intervention in consultation with service users
(2019-12)Guided imagery interventions have a range of applications to affect emotion, thought and behaviour. They may be effectively used by staff with minimal training and are simple and quick to use. Service user involvement ... -
Developing an automated VR cognitive treatment for psychosis: gameChange VR therapy
(2020-04)The automated delivery of psychological treatment using virtual reality (VR) has the potential to revolutionise patient access to evidence-based care. VR creates immersive, interactive computer simulations, which elicit ... -
Developing Clinical Guidelines for Dietitians Treating Young People with Anorexia Nervosa - Family Focused Approach Working Alongside Family Therapists
(2019-05)Introduction: Family therapy for the treatment of Anorexia Nervosa (AN) in an outpatient setting is the evidenced based model of care. Nutritional intervention is an essential component in the treatment of AN particularly ... -
Development and implementation of the physiotherapy-led exercise interventions for the treatment of rotator cuff disorders for the ‘Getting it Right: Addressing Shoulder Pain’ (GRASP) trial
(2019-07)Objectives: The Getting it Right: Addressing Shoulder Pain (GRASP) trial is a large-scale, multicentre, 2 × 2 factorial randomised controlled trial investigating clinical and cost-effectiveness of a progressive exercise ... -
Development and validation of a prediction model for the probability of responding to placebo in antidepressant trials: a pooled analysis of individual patient data
(2019-02)Background: Identifying potential placebo responders among apparent drug responders is critical to dissect drug-specific and nonspecific effects in depression. Objective: This project aimed to develop and test a prediction ... -
Development of a core outcome set for lower limb orthopaedic surgical interventions in ambulant children and young people with cerebral palsy: a study protocol
(2020-03)Introduction Musculoskeletal deformities and gait deviations are common features in ambulatory cerebral palsy (CP). Deformity correction through lower limb orthopaedic surgery is the standard form of care aimed at improving ... -
Development of A Guideline for Reporting Mediation Analyses (AGReMA)
(2020-02)There are a growing number of studies using mediation analysis to understand the mechanisms of health interventions and exposures. Recent work has shown that the reporting of these studies is heterogenous and incomplete. ... -
Development of an app for lung cancer survivors (iEXHALE) to increase exercise activity and improve symptoms of fatigue, breathlessness and depression
(2019-11)Objective Exercise‐based self‐management interventions are recommended for lung cancer survivors and can provide physical, psychosocial and emotional relief. Mobile health technologies can encourage self‐management; ... -
Development of the Ketamine Side Effect Tool
(2020-04)Background: Currently, no specific, systematic assessment tool for the monitoring and reporting of ketamine-related side effects exists. Our aim was to develop a comprehensive Ketamine Side Effect Tool (KSET) to capture ... -
Diagnosis Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Syndrome
(2019-12)IMPORTANCE: Atypical parkinsonian syndromes (APS), including progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), and multiple system atrophy (MSA), may be difficult to distinguish in early stages and are ... -
Diagnostic accuracy and clinical impact of natriuretic peptide screening for the detection of heart failure in the community: a protocol for systematic review and meta-analysis [version 2; peer review: awaiting peer review]
(2019-12)Introduction: Patients diagnosed with heart failure in primary care have a better prognosis than those diagnosed in hospital. However, most cases are missed in the community. Recent attention has focussed on the potential ... -
The different influence of high levels of physical activity on the incidence of knee OA in overweight and obese men and women-a gender specific analysis
(2019-10)Objective To investigate the influence of physical activity on incidence of knee osteoarthritis (OA) in overweight and obese men and women. Design Data were extracted from the Osteoarthritis Initiative cohort on 1,667 ... -
Different Types and Acceptability of Psychotherapies for Acute Anxiety Disorders in Children and Adolescents: A Network Meta-analysis
(2018-10)Anxiety disorders are common in children and adolescents, and uncertainty remains regarding the optimal strategy of psychotherapies in this population. OBJECTIVE: To compare and rank the different types of psychotherapies ... -
Differential effects of poor recall and memory disjointedness on trauma symptoms
(2018)Clinical theories of PTSD suggest that trauma memories are disorganised. The present study examined how trauma film exposure affects two aspects of memory disorganisation, poor memory recall and memory disjointedness, and ... -
Difficult conversations? Engaging patients in reducing waste in health care
(2016)Purpose – Reducing waste in health care can result in savings that could be used to meet the projected shortfall in NHS funding or to meet the care needs of vulnerable groups. Patients and their families can contribute ... -
Digital Cognitive Behavioral Therapy for Insomnia for Adolescents With Mental Health Problems: Feasibility Open Trial
(2020-03)Background: Insomnia in adolescents is common, persistent, and associated with poor mental health including anxiety and depression. Insomnia in adolescents attending child mental health services is seldom directly treated, ...
