ORKA
The Oxford Health Research & Knowledge Archive (ORKA) is the online showcase for Oxford Health NHS Foundation Trust research.
ORKA is managed by Oxford Health Libraries. Please contact library.enquiries@oxfordhealth.nhs.uk for further information.
Oxford Health Research & Knowledge Archive
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Recently Added
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Are current guidelines overcautious regarding refeeding of patients with severe anorexia nervosa: a retrospective cohort study
(2020-05)Weight restoration is an integral part of managing anorexia nervosa patients and has been found to be associated with electrolyte and fluid abnormalities gathered under the umbrella term refeeding syndrome, which has led ... -
The Western diet: a blind spot of eating disorder research?—a narrative review and recommendations for treatment and research
(2020-07)Over the last 50 years, in parallel with the obesity epidemic, the prevalence of eating disorders has increased and presentations have changed. In this narrative review, we consider recent research exploring the implications ... -
Ultra-processed foods and binge eating: A retrospective observational study
(2021-04)There is increasing evidence of the impact of ultra-processed foods on multiple metabolic and neurobiological pathways, including those involved in eating behaviors, both in animals and in humans. In this study we aimed ... -
Evolutionary Perspectives on Eating Disorders
(2022-09)The focus of this chapter is on evolutionary theories and models of anorexia nervosa (AN), bulimia nervosa (BN) and obesity. Although obesity is not considered a mental health problem, its link with binge eating disorder ... -
EATING DISORDERS: AGE OF ONSET AND ITS ASSOCIATED GENETIC RISK FACTORS
(2022-09)The age at which an eating disorder begins to develop has important implications for the design of services and the targeting of clinical interventions. Eating disorders have a heritability of 16-83% and a median age ... -
Are mothers who stay with their physically violent partners failing to protect their children?
(2023-07)Tensions exist between the perceived roles and responsibilities of the protective mother, and the lived experiences of mothers in domestic abusive relationships. This paper challenges the prejudices faced by mothers by ... -
Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder
(2023-07)JNJ-54175446 is a selective purine P2X7 receptor (P2X7R) antagonist that attenuates microglial IL-1β/IL-18 release. In healthy volunteers, JNJ-54175446 suppressed peripheral interleukin (IL)-1β release, and attenuated ... -
Nasogastric tube feeding under restraint: understanding the impact and improving care
(2023-07)Nasogastric tube feeding under physical restraint is an intervention that clinicians working in specialist mental health in-patient units may need to implement. Aims To examine the impact of this intervention on people ...