Browsing by Title
Now showing items 218-237 of 591
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Factors associated with fatigue in CNS inflammatory diseases with AQP4 and MOG antibodies
(2020-02)Objective: Fatigue is a common and disabling symptom amongst people withmultiple sclerosis, however it has not been compared across the central nervoussystem (CNS) inflammatory diseases associated with aquaporin-4 (AQP4) ... -
Factors associated with the prescribing of high-dose opioids in primary care: a systematic review and meta-analysis
(2020-03)Background The risks of harms from opioids increase substantially at high doses, and high-dose prescribing has increased in primary care. However, little is known about what leads to high-dose prescribing, and studies ... -
Factors influencing the implementation of self-management solutions in healthcare: an interview study with NHS managers
(2020-03)Background/aims: Research focusing on the perspectives of healthcare managers, who are often key in devising strategies for the implementation of self-management solutions, is limited. This study aimed to investigate the ... -
Fear of illness recurrence and mental healthanxiety in people recovering from psychosis andcommon mental health problems
(2020-06)Objectives: It is well known that mental health problems can recur even after effective treatment, leading to an understandable fear of illness recurrence (FIR) and mental health anxiety (MHA). These may themselves contribute ... -
Fit to Study: Reflections on designing and implementing a large-scale randomized controlled trial in secondary schools
(2020-09)Background The randomised controlled trial (RCT) design is increasingly common among studies seeking good-quality evidence to advance educational neuroscience, but conducting RCTs in schools is challenging. Fit to Study, ... -
Five models for child and adolescent data linkage in the UK: a review of existing and proposed methods
(2020-02)Over the last decade dramatic advances have been made in both the technology and data available to better understand the multifactorial influences on child and adolescent health and development. This paper seeks to ... -
A framework synthesis reviewing the impact of neonatal care unit admission on early caregiver–infant relationships
(2020-10)Aims To critically review and synthesize qualitative research pertaining to the establishment of early caregiver–infant relationships in the neonatal care unit (NCU). Background It is well‐established that bonding and ... -
Frequency of Self-reported Unpleasant Events and Harm in a Mindfulness-Based Program in Two General Population Samples
(2020-12)Objectives Evidence-based mindfulness programs have well-established benefits, but the potential for harmful effects is understudied. We explored the frequency and severity of unpleasant experiences and harm in two ... -
Functional biases in attentional templates from associative memory
(2020-12)In everyday life, attentional templates—which facilitate the perception of task-relevant sensory inputs—are often based on associations in long-term memory. We ask whether templates retrieved from memory are necessarily ... -
The Functional Consequences of Social Attention for Memory-guided Attention Orienting and Anticipatory Neural Dynamics
(2019-02)Social attention when viewing natural social (compared to non-social) images has functional consequences on contextual memory in healthy human adults. In addition to attention affecting memory performance, strong evidence ... -
Functional organisation for verb generation in children with developmental language disorder
(2020-12)Developmental language disorder (DLD) is characterised by difficulties in learning one's native language for no apparent reason. These language difficulties occur in 7% of children and are known to limit future academic ... -
G251(P) Quality improvement in training: establishing a paediatric-CAMHS collaborative learning programme
(2019-05)Introduction: Recent reports have suggested that nearly a quarter of girls aged 14 have self-harmed in the past year, and newspapers report a ‘crisis in children’s mental health’.1 With paediatricians seeing many more ... -
Gamifying Bioethics: A Case Study of Co-Designing Empirical Tools with Adolescents
(2020-07)Research in bioethics largely relies on interviews and surveys, which engage participants with scenarios that are distal in time and place to an actual situation. However, context and embodiment are relevant to moral ... -
GDm‐Health Plus: Development of a remote behavioural lifestyle management system for women with gestational diabetes
(2018-03)Aim: Preventing hyperglycaemia and excessive gestational weight gain through diet and physical activity are central to the management of women with gestational diabetes (GDM), although lifestyle change can be challenging. ... -
Generating comparative evidence on new drugs and devices before approval
(2020-03)Fewer than half of new drugs have data on their comparative benefits and harms against existing treatment options at the time of regulatory approval in Europe and the USA. Even when active-comparator trials exist, they ... -
Genetics of self-reported risk-taking behaviour, trans-ethnic consistency and relevance to brain gene expression
(2018)Risk-taking behaviour is an important component of several psychiatric disorders, including attention-deficit hyperactivity disorder, schizophrenia and bipolar disorder. Previously, two genetic loci have been associated ... -
The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function
(2019)Genome-wide association studies (GWAS) of psychiatric phenotypes have tended to focus on categorical diagnoses, but to understand the biology of mental illness it may be more useful to study traits which cut across traditional ... -
Global prevalence and risk factors for mental health problems in police personnel: a systematic review and meta-analysis
(2020-05)Police face an increased risk of developing mental health problems, yet reliable estimates of their psychological difficulties remain unknown. This systematic review and meta-analysis estimate the pooled prevalence and ... -
Glucocorticoid ultradian rhythmicity differentially regulates mood and resting state networks in the human brain: A randomised controlled clinical trial
(2021-02)Adrenal glucocorticoid secretion into the systematic circulation is characterised by a complex rhythm, composed of the diurnal variation, formed by changes in pulse amplitude of an underlying ultradian rhythm of short ... -
Harnessing mobile devices to support the delivery of community-based clinical care: a participatory evaluation
(2019)Background:A large provider of community health services (an NHS Trust in England) deployed Apple iPads to its front-line community-based healthcare clinicians (predominantly nurses) to enable them to increase responsiveness ...
