Background The risks of harms from opioids increase substantially at high doses, and high-dose prescribing has increased in primary care. However, little is known about what leads to high-dose prescribing, and studies ...

Social attention when viewing natural social (compared to non-social) images has functional consequences on contextual memory in healthy human adults. In addition to attention affecting memory performance, strong evidence ...

Aim: Preventing hyperglycaemia and excessive gestational weight gain through diet and physical activity are central to the management of women with gestational diabetes (GDM), although lifestyle change can be challenging. ...

Genome-wide association studies (GWAS) of psychiatric phenotypes have tended to focus on categorical diagnoses, but to understand the biology of mental illness it may be more useful to study traits which cut across traditional ...

The role of doctors will undoubtedly evolve as knowledge, and perverse ignorance become more universally available to all via the internet. The role of the psychiatrist must be to relate real advances in understanding ...

Key learning points: For many young people, the function of self-harm is to escape an unbearable emotional state; relief and negative feelings experienced following self-harm can result in a cycle of self-harming behaviour; ...

Over the past three decades, MRI has become a key tool to study how cognitive processes are implemented in the human brain. However, the question of whether participants recruited into MRI studies differ from participants ...

Introduction: In patients with schizophrenia, medication adherence is important for relapse prevention, and effective adherence monitoring is essential for treatment planning. A digital medicine system (DMS) has been ...

People with bipolar disorder are particularly vulnerable to anxiety and intrusive mental imagery, which can contribute to mood swings and a heightened risk for relapse. This book presents a novel brief treatment that focuses ...

There is debate in the literature as to whether inclusion of a placebo arm may alter characteristics of antidepressant trials. However, previous research has focused on response rates of various antidepressants on average ...