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Now showing items 550-569 of 1185
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Induced pluripotent stem cells in psychiatry: a critical review
(2021-01)A key challenge in psychiatry research is the development of high-fidelity model systems that can be experimentally manipulated to explore and test pathophysiological mechanisms of illness. In this respect, the emerging ... -
Inducing Affective Learning Biases with Cognitive Training and Prefrontal tDCS: A Proof-of-Concept Study
(2020-10)Cognitive models of mood disorders emphasize a causal role of negative affective biases in depression. Computational work suggests that these biases may stem from a belief that negative events have a higher information ... -
Infant mental health and the role of the health visitor
(2023-09)The theme for June's infant mental health week this year was ‘Bonding before birth’, with organisations sharing the importance of support for parents and carers to enable them to understand baby brain development and how ... -
The influence of perceived accessibility and expertise of healthcare professionals, and service austerity, on mothers' decision-making
(2020-07)Mothers often make key decisions regarding their children's health. They hold core beliefs and attitudes towards healthcare providers, relying on healthcare services to provide sup-port, advice and reassurance. It is crucial ... -
Information Extraction from Swedish Medical Prescriptions with Sig-Transformer Encoder
(2020-10)Relying on large pretrained language models such as Bidirectional Encoder Representations from Transformers (BERT) for encoding and adding a simple prediction layer has led to impressive performance in many clinical natural ... -
Informing National Health Service patients about participation in clinical research: A comparison of opt-in and opt-out approaches across the United Kingdom
(2020-11)Objective: Recruitment to clinical research in the National Health Service remains challenging. One barrier is accessing patients to discuss research participation. Two general approaches are used in the United Kingdom ... -
Initial treatment choices to achieve sustained response in major depression: a systematic review and network meta-analysis
(2021-10)Major depression is often a relapsing disorder. It is therefore important to start its treatment with therapies that maximize the chance of not only getting the patients well but also keeping them well. We examined the ... -
Injection fears and COVID-19 vaccine hesitancy
(2021-06)When vaccination depends on injection, it is plausible that the blood-injection-injury cluster of fears may contribute to hesitancy. Our primary aim was to estimate in the UK adult population the proportion of COVID-19 ... -
Innovations in Practice: Avatar-based virtual reality in CAMHS talking therapy: two exploratory case studies
(2019-03)Background: Avatar-based virtual reality therapy is an emerging digital technology that can be used to assist the treatment of common mental health problems. This may be particularly appealing to young people who are ... -
Insomnia as a mediating therapeutic target for depressive symptoms: A sub-analysis of participant data from two large randomized controlled trials of a digital sleep intervention
(2020-06)Insomnia predicts the onset of depression, commonly co-presents with depression and often persists following depression remission. However, these conditions can be challenging to treat concurrently using depression-specific ... -
Integrated Enhanced Cognitive Behavioural (I-CBTE) therapy significantly improves effectiveness of inpatient treatment of anorexia nervosa in real life settings
(2022-01)Inpatient treatment of anorexia nervosa (AN) often results in poor outcomes. To address this, the Oxford service has adapted the multistep enhanced cognitive behavioural (CBTE) treatment model, first developed in Italy, ... -
Integrating static and modifiable risk factors in violence risk assessment for forensic psychiatric patients: a feasibility study of FoVOx
(2022-06)Introduction: Risk assessment is integral to forensic psychiatry. Previous work has highlighted the benefits of using scalable and evidence-based actuarial risk tools developed within forensic populations, such as the ... -
International Multicenter Analysis of Brain Structure Across Clinical Stages of Parkinson’s Disease
(2021-06)ABSTRACT: Background: Brain structure abnormalities throughout the course of Parkinson’s disease have yet to be fully elucidated. Objective: Using a multicenter approach and harmonized analysis methods, we aimed to shed ... -
Internet-Based Cognitive Therapy for Social Anxiety Disorder in Hong Kong: Therapist Training and Dissemination Case Series
(2019-02)Background: Guided internet-based psychological interventions show substantial promise for expanding access to evidence-based mental health care. However, this can only be achieved if results of tightly controlled studies ... -
Internet-delivered cognitive therapy for social anxiety disorder in Hong Kong: A randomized controlled trial
(2022-04)Research is needed to determine the extent to which internet-delivered psychological therapies are effective when delivered in countries and cultures outside of where they were developed. Objective This waitlist-controlled ... -
An Interpretative Phenomenological Analysis exploring how psychiatrists conceptualise conduct disorder and experience making the diagnosis
(2020-10)The way professionals conceptualise CD likely impacts the identity of children given the diagnosis, yet how psychiatrists conceptualise CD, and experience making the diagnosis, is under-researched. Interpretative ... -
An interprofessional practice development group for newly qualified and new-to-role clinicians in community mental health
(2019-11)There is a wealth of literature focusing on the transition from being a new graduate to being a newly qualified member of staff. However, the needs of the new-to-role practitioner, who may be expected to manage challenging ... -
Interventions and strategies aimed at clinical academic pathway development for nurses in the United Kingdom: A systematised review of the literature
(2021-01)Aims and objectives To review interventions and strategies designed to progress UK clinical academic career pathways in nursing and identify barriers and facilitators to aid wider implementation. Background For over a ... -
Interventions to reduce self-harm on in-patient wards: systematic review
(2021-04)Background Incidents of self-harm are common on psychiatric wards. There are a wide variety of therapeutic, social and environmental interventions that have shown some promise in reducing self-harm in in-patient settings, ... -
Intravenous immunoglobulin and rituximab versus placebo treatment of antibody-associated psychosis: study protocol of a randomised phase IIa double-blinded placebo-controlled trial (SINAPPS2)
(2019-06)Background: Evidence is conflicting about a causal role of inflammation in psychosis and, specifically, regarding antibodies binding to neuronal membrane targets, especially N-methyl-D-aspartate receptors. NMDAR, LGI1 and ...