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Now showing items 287-306 of 1185
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Digitally augmented, parent-led CBT versus treatment as usual for child anxiety problems in child mental health services in England and Northern Ireland: a pragmatic, non-inferiority, clinical effectiveness and cost-effectiveness randomised controlled trial
(2024-03)Anxiety problems are common in children, yet few affected children access evidence-based treatment. Digitally augmented psychological therapies bring potential to increase availability of effective help for children with ... -
Digitally supported CBT to reduce paranoia and improve reasoning for people with schizophrenia-spectrum psychosis: the SlowMo RCT
(2021-08)Background: Reasoning may play a causal role in paranoid delusions in psychosis. SlowMo, a new digitally supported cognitive–behavioural therapy, targets reasoning to reduce paranoia. Objectives: To examine the effectiveness ... -
Direct costs of hospital care of self-harm: A national register-based cohort study
(2021-11)Objective To estimate national direct hospital costs associated with treatment of self-harm and to analyse whether costs differ with respect to demographic and clinical characteristics. Methods A cohort design was applied ... -
Discharge pathways and relapse following treatment from early intervention in psychosis services
(2018-04)Early intervention in psychosis (EIP) services are the dominant service model in the treatment of first-episode psychosis. They are a time-limited intervention and little is known about discharge destinations and outcomes ... -
The Disease Influenced Vaccine Acceptance Scale-Six (DIVAS-6): Validation of a Measure to Assess Disease-Related COVID-19 Vaccine Attitudes and Concerns
(2022-06)Patients with underlying comorbidities are particularly vulnerable to poor outcomes from SARS-CoV-2 infection. Despite the context-specific nature of vaccine hesitancy, there are currently no scales that incorporate disease ... -
Disentangling the Consequences of Systemic Racism and Clinical Paranoia to Promote Effectiveness of a Cognitive-Behavioral Intervention for Persecutory Delusions in Minoritized Individuals: A Case-Example
(2023-07)While everyone experiences threats, some threats are culturally specific and not universally recognized or addressed by providers. A prominent example is threat-based worry and hypervigilance in Black Americans and other ... -
Disrupted‐in‐schizophrenia 1 functional polymorphisms and D2/D3 receptor availability: A [11C]‐(+)‐PHNO imaging study
(2019-07)The disrupted‐in‐schizophrenia 1 (DISC1) protein has been implicated in a range of biological mechanisms underlying chronic mental disorders such as schizophrenia. Schizophrenia is associated with abnormal striatal dopamine ... -
Disrupting the power balance between doctors and patients in the digital era
(2021-01)The primary way of identifying symptoms of impending disease, and when it is time to seek care, relies heavily on a patient's own perception of how they feel. This reliance on a disease reaching a threshold at which ... -
Dissecting Transient Burst Events
(2020-10)Increasing efforts are being made to understand the role of intermittent, transient, high-power burst events of neural activity. These events have a temporal, spectral, and spatial domain. Here, we argue that considering ... -
Dissociating Spatial Attention from Neglect Dyslexia: a Single Case Study
(2020-06)Word-centred neglect dyslexia is generally thought to be caused by a visuospatial neglect-like attentional deficit which impacts orientation-canonical representations of visual stimuli. However, the relationship between ... -
Dissociation in patients with non-affective psychosis: Prevalence, symptom associations, and maintenance factors
(2021-11)Dissociation is problematic in its own right for patients with psychosis but may also contribute to the occurrence of psychotic experiences. We therefore set out to estimate in a large cohort of patients with psychosis the ... -
Dissociation in relation to other mental health conditions: An exploration using network analysis
(2020-08)Dissociative experiences, traditionally studied in relation to trauma and PTSD, may be important phenomena across many different psychological conditions, including as a contributory causal factor for psychotic experiences. ... -
A Dissociation of the Acute Effects of Bupropion on Positive Emotional Processing and Reward Processing in Healthy Volunteers
(2018-10)Background: Previous research indicates that antidepressants can restore the balance between negative and positive emotional processing early in treatment, indicating a role of this effect in later mood improvement. However, ... -
Do communication interventions affect the quality-of-life of people with dementia and their families? A systematic review
(2023-04)Speech, language and communication difficulties are prevalent in all dementia subtypes and are likely to considerably impact the quality-of-life of people with dementia and their families. Communication interventions ... -
Do environmental risk factors for the development of psychosis distribute differently across dimensionally assessed psychotic experiences?
(2021-04)Psychotic experiences (PE) are associated with poorer functioning, higher distress and the onset of serious mental illness. Environmental exposures (e.g. childhood abuse) are associated with the development of PE. However, ... -
‘Do not attempt cardiopulmonary resuscitation’ (DNACPR)—difficulty in discussions with older medical inpatients and their families: a survey of hospital doctors
(2021-07)Objectives To determine, for doctors looking after older medical inpatients: (1) how difficult they find discussions about ‘do not attempt cardiopulmonary resuscitation’ (DNACPR); (2) whether difficulty is associated with ... -
Do parent factors predict early weight gain in family therapy for anorexia nervosa? Revisiting variables in a community treatment sample
(2020-12)Objective: It is unclear why some children and adolescents respond well to family therapy for anorexia nervosa (AN) and others do not. Previous exploratory studies have suggested that parent variables may be important ... -
Do sagittal spinal curvature and back extensor endurance correlate with gait and balance measures in people with degenerative spinal conditions?
(2022-02)The aim was to investigate the relationship between sagittal spinal curvature and endurance with dynamic balance and gait in people with symptomatic degenerative spinal conditions. Methods: In this cohort study, participants ... -
Do they really care? Specificity of social support issues in hoarding disorder and obsessive-compulsive disorder
(2023-05)Objectives: Unmet interpersonal needs may play a role in excessive emotional attachments to objects for people with hoarding disorder (HD). Previous research indicates that social support (but not attachment difficulties) ... -
Does adjunctive digital CBT for insomnia improve clinical outcomes in an improving access to psychological therapies service?
(2021-09)Insomnia has a bidirectional relationship with broader mental health functioning, including anxiety and depression. Yet, poor sleep has historically been neglected as a specific treatment target in mental health programmes ...