Browsing Conditions by Title
Now showing items 126-145 of 698
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Computer-vision aided functional movement measurement in people with and without axial spondyloarthritis – validation and feasibility study protocol
(2021-11)Back pain is a common form of disability worldwide,and one condition that causes chronic back pain is axial spondyloarthritis (axSpA) which primarily affects spinal joints resulting in pain and joint stiffness. There ... -
Conceptual Framework for an Episode of Rehabilitative Care After Surgical Repair of Hip Fracture
(2019-03)Researchers face a challenge when evaluating the effectiveness of rehabilitation after a surgical procedure for hip fracture. Reported outcomes of rehabilitation will vary depending on the end point of the episode of care. ... -
Connections Between Insomnia and Cognitive Aging.
(2019-06)Insomnia is a common sleep disorder among older adults, and a risk factor for poor physical and mental health. However, the relationship between insomnia and cognitive health is not well understood. Here, we review ... -
Considerations in the assessment of capacity
(2020-10)The right of autonomous patients to make decisions about their care is core to medical practice. However, we are frequently faced with situations where a patient is unable to make those decisions because of their medical ... -
A Content Analysis and Comparison of Two Peaks of Newspaper Reporting During a Suicide Cluster to Examine Implications for Imitation, Suggestion, and Prevention
(2020-03)During 2007–2008, media attention focused on a cluster of youth suicides in the UK. There were two peaks (P1, P2) in the volume of newspaper reporting of the deaths. The number of possible suicides was greater than expected ... -
A continuum hypothesis of psychotomimetic rapid antidepressants
(2021-05)Ketamine, classical psychedelics and sleep deprivation are associated with rapid effects on depression. Interestingly, these interventions also have common psychotomimetic actions, mirroring aspects of psychosis such as ... -
The Convergent Validity of the electronic Frailty Index (eFI) with the Clinical Frailty Scale (CFS)
(2020-11)Background: Different scales are being used to measure frailty. This study examined the convergent validity of the electronic Frailty Index (eFI) with the Clinical Frailty Scale (CFS). Method: The cross-sectional study ... -
Coproduction with Autistic Adults: Reflections from the Authentistic Research Collective
(2020-12)This article explores coproduction in relation to autistic people. We reflect on the coproduction process with autistic adults from the Authentistic Research Collective at University College London. We aimed to support the ... -
Cost and quality-of-life impacts of community treatment orders (CTOs) for patients with psychosis: economic evaluation of the OCTET trial
(2020-07)Purpose:Current RCT and meta-analyses have not found any effect of community treatment orders (CTOs) on hospital or social outcomes. Assumed positive impacts of CTOs on quality-of-life outcomes and reduced hospital costs ... -
The costs of bipolar disorder in the United Kingdom
(2021-09)Objectives: To estimate the individual cost and population-level economic burden of Bipolar Disorder (BD), and explore the impact of clinical and sociodemographic factors on costs in the United Kingdom. Methods: Annual ... -
COVID and early intervention: the impact of COVID-19 on referrals to an early intervention service
(2021-06)COVID-19 has a demonstratable impact on the population's mental health and is associated with an increased incidence of psychiatric disorders, including patients experiencing psychotic presentations. The aim of this study ... -
Covid-19 and mental health: a transformational opportunity to apply an evidence-based approach to clinical practice and research
(2020-04)The Oxford Precision Psychiatry Lab (https://oxfordhealthbrc.nihr.ac.uk/our-work/oxppl/, @OxfordPPL) collected from senior clinicians in the local Mental Health Trust a list of specific and focused questions about mental ... -
COVID-19 and substance use disorders: a review of international guidelines for frontline healthcare workers of addiction services
(2022-03)People with substance use disorders may be at a greater risk of contracting COVID-19 infection and developing medical complications. Several institutional and governmental health agencies across the world developed ad hoc ... -
COVID-19 vaccine hesitancy in systemic sclerosis
(2021-07)In conclusion, our survey suggests that most patients with SSc have positive feelings towards COVID-19 vaccine, but uncertainties are present in a considerable proportion of cases. These results highlight the crucial ... -
COVID-19 vaccines, hesitancy and mental health
(2021-04)‘None of us will be safe until everyone is safe. Global access to coronavirus vaccines, tests and treatments for everyone who needs them, anywhere, is the only way out’. This statement by Dr Tedros Adhanom Ghebreyesus, ... -
COVID-19, mental health and ethnic minorities
(2020-07)There is little formal guidance for the busy clinician in balancing different risks for individual mental health patients and treating appropriately. To fill this gap, we propose three core actions that may help: 1. ... -
Creating a care pathway for patients with longstanding, complex eating disorders
(2022-08)Recovery rates for people with eating disorders are low; fewer than half recover and approximately 20% develop a longstanding eating disorder. Patients with longstanding eating disorders are often referred to as “SEED” ... -
Critical Developmental Windows of Voltage-Gated Cation Channel Expression in Psychiatric Disorders
(2021-09)The molecular underpinnings of psychiatric disorders remain elusive despite there being a paramount need to establish druggable targets for their treatment. Genome-wide association studies (GWASs) have identified numerous ... -
CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice
(2019-08)Neuroinflammation and microglial activation are significant processes in Alzheimer’s disease pathology. Recent genome-wide association studies have highlighted multiple immune-related genes in association with Alzheimer’s ... -
Cyclical Cushing's syndrome and the presentation of a Bipolar Affective state
(2019-12)Affective disorders are relatively frequently observed in patients suffering from endocrine disease. Thus, in Cushing's syndrome, the most common comorbid mental disorder seen is depressive disorder. The rarer cyclical ...