Conditions, Lifestyle Factors & Interventions
Recent Submissions
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Age-related response speed deficits arise from specific impairments in sensory evidence accumulation rate
(2021-11)Older adults exposed to enriched environments (EE) maintain relatively higher levels of cognitive function, even in the face of compromised markers of brain health. Response speed (RS) is often used as a simple proxy to ... -
Accurate expression quantification from nanopore direct RNA sequencing with NanoCount
(2021-11)Accurately quantifying gene and isoform expression changes is essential to understanding cell functions, differentiation and disease. Sequencing full-length native RNAs using long-read direct RNA sequencing (DRS) has the ... -
Neurons derived from individual early Alzheimer’s disease patients reflect clinical vulnerability
(2021-11)Modelling sporadic Alzheimer’s disease (sAD) with patient-derived induced pluripotent stem cells (iPSCs) is challenging yet remains an important step in understanding the disease. Here we report a novel approach of sAD ... -
Motivational Interviewing-based interventions for reducing substance misuse and increasing treatment engagement, retention, and completion in the homeless populations of high-income countries: An equity-focused systematic review and narrative synthesis
(2021-11)Rising mortality and disease prevalence in the homeless have been largely attributed to addiction disorders. This review aimed to assess whether Motivational Interviewing (MI) is effective in changing substance misuse ... -
Understanding health anxiety in the COVID-19 pandemic
(2021-11)The COVID-19 pandemic continues to be one of the greatest public health challenges faced by the UK. Reported rates of psychiatric difficulties have increased and the mechanisms by which the pandemic has affected mental ... -
Roadblock: improved annotations do not necessarily translate into new functional insights
(2021-11)The advent of cost-effective high-throughput nucleotide sequencing means that information about the transcriptome is accruing at an exponential rate, rapidly refining our understanding of the diversity of gene products. ... -
Direct costs of hospital care of self-harm: A national register-based cohort study
(2021-11)Objective To estimate national direct hospital costs associated with treatment of self-harm and to analyse whether costs differ with respect to demographic and clinical characteristics. Methods A cohort design was applied ... -
Exercise versus usual care after non-reconstructive breast cancer surgery (UK PROSPER): multicentre randomised controlled trial and economic evaluation
(2021-11)Objective To evaluate whether a structured exercise programme improved functional and health related quality of life outcomes compared with usual care for women at high risk of upper limb disability after breast cancer ... -
Use of online cultural content for mental health and well-being during COVID-19 restrictions: cross-sectional survey
(2021-11)Aims and method To gain a deeper understanding of the use of online culture and its potential benefits to mental health and well-being, sociodemographic characteristics and self-reported data on usage, perceived mental ... -
Investigating Different Levels of Bimanual Interaction With a Novel Motor Learning Task: A Behavioural and Transcranial Alternating Current Stimulation Study
(2021-11)In everyday life, we perform countless movements with our hands. Some, such as writing, drawing, or eating with chopsticks, require one hand alone, whereas others require the skilled interaction of both hands. For bimanual ... -
A between-task consequence of temporal expectations
(2021-11)In everyday life, we often anticipate the timing of one upcoming task or event while actively engaging in another. Here, we investigated temporal expectations within such a multi-task scenario. In a visual working-memory ... -
A web-based life-style, exercise and activity intervention for people with progressive multiple sclerosis: Results of a single-arm feasibility study
(2021-11)Background People with progressive Multiple Sclerosis often struggle to access appropriate and inclusive support for regular physical activity. The Lifestyle, Exercise and Activity Package (LEAP-MS) intervention, is a ... -
No antidepressant-like acute effects of bright light on emotional information processing in healthy volunteers
(2021-11)Rationale: Bright light treatment (BLT) is an efficacious antidepressant intervention, but its mechanism of action is not well understood. Antidepressant drugs acutely affect how emotional information is processed, pushing ... -
Over-the-counter analgesics use is associated with pain and psychological distress among adolescents: a mixed effects approach in cross-sectional survey data from Norway
(2021-11)Over-the-counter analgesics (OTCA) such as Paracetamol and Ibuprofen are frequently used by adolescents, and the route of administration and access at home allows unsupervised use. Psychological distress and pain occur ... -
Knowledge and Use of Novel Psychoactive Substances in Italy: a Survey-Based Study in the General Population
(2021-11)In this study, we aimed to identify the current trend of novel psychoactive substance (NPS) consumption in Italy and the level of knowledge about NPS in the general population and to explore the presence of risk factors ... -
Computer-vision aided functional movement measurement in people with and without axial spondyloarthritis – validation and feasibility study protocol
(2021-11)Back pain is a common form of disability worldwide,and one condition that causes chronic back pain is axial spondyloarthritis (axSpA) which primarily affects spinal joints resulting in pain and joint stiffness. There ... -
Dissociation in patients with non-affective psychosis: Prevalence, symptom associations, and maintenance factors
(2021-11)Dissociation is problematic in its own right for patients with psychosis but may also contribute to the occurrence of psychotic experiences. We therefore set out to estimate in a large cohort of patients with psychosis the ... -
Women in psychiatry and women's mental health
(2021-11)Women are increasingly well represented in psychiatry as a profession, but data show us that it is not a level playing eld. Written by the Chairs of the Women and Mental Health Special Interest Group (WMHSIG) of the Royal ... -
Substance use disorder treatment success: assessing patient-reported use improvement and provider-evaluated treatment completion
(2021-11)Provider-evaluated substance use treatment completion and client-reported substance use improvement are standards in determining treatment success. The relationship between these two outcomes is anecdotally understood in ... -
Abstract thinking as a risk factor for the development of posttraumatic stress disorder symptoms in student paramedics
(2021-10)Abstract cognitive processing is characterized by “why?” and “what if?” questions and associated with processes such as rumination and worry. The tendency to think abstractly in response to stress has not been examined as ...
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