Conditions, Lifestyle Factors & Interventions
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Visual fixation patterns during economic choice reflect covert valuation processes that emerge with learning
(2019-10)Visual fixations play a vital role in decision making. Recent studies have demonstrated that the longer subjects fixate an option, the more likely they are to choose it. However, the role of evaluating stimuli covertly ... -
Impulse control disorders in Parkinson disease and RBD
(2019-10)Objective To describe the prevalence, natural history, and risk factors for impulse control behaviors (ICBs) among people with Parkinson disease (PD), those with REM sleep behavior disorder (RBD), and controls. Metho ... -
ENIGMA MDD: Seven Years of Global Neuroimaging Studies of Major Depression through Worldwide Data Sharing
(2019-10)A key objective in the field of translational psychiatry over the past few decades has been to identify the brain correlates common to individuals with major depressive disorder (MDD). Identifying measurable indicators ... -
Supported decision making for people with mental health disorders in clinical practice: a systematic review.
(2019-10)Objectives: The Convention on the Rights of Persons with Disabilities (CRPD) was adopted at the United Nations Assembly in 2006. The main aim of the convention is to ensure equal rights for people with disabilities including ... -
Why Health Care Professionals Belong to an Intensive Care Virtual Community: Qualitative Study
(2019-11)Background: Clinical practice variation that results in poor patient outcomes remains a pressing problem for health care organizations. Some evidence suggests that a key factor may be ineffective internal and professional ... -
Prospective task knowledge improves working memory-guided behaviour
(2019-07)Working memory (WM) is the ability to keep information online for a forthcoming task. WM theories have tended to focus on how sensory information is maintained, and less on how WM content is used for guiding behaviour. ... -
Predicting motor, cognitive & functional impairment in Parkinson’s
(2019-07)Objective: We recently demonstrated that 998 features derived from a simple 7-minute smartphone test could distinguish between controls, people with Parkinson’s and people with idiopathic Rapid Eye Movement sleep behavior ... -
Variation in spend on young mental health across Clinical Commissioning Groups in England: a cross-sectional observational study
(2019-08)Objectives To investigate whether the rate of spend on child and adolescent mental health is influenced by demand for other competing services in local commissioning decisions. Design Analysis of spend data by Clinical ... -
The Salt Swap intervention to reduce salt intake in people with high blood pressure: protocol for a feasibility randomised controlled trial
(2019-10)Background: High salt intake is a risk factor for hypertension and cardiovascular disease. Reducing salt intake has been shown to reduce blood pressure. Despite population-level interventions, including product reformulation ... -
Self-reported depression symptoms in haemodialysis patients: Bi-factor structures of two common measures and their association with clinical factors
(2018-08)Objective: To validate the factor structure of two common self-report depression tools in a large sample of haemodialysis (HD) patients and to examine their demographic and clinical correlates, including urine output, ... -
Value of monitoring negative emotional bias in primary care in England for personalised antidepressant treatment: a modelling study
(2019-11)Depressed patients often focus on negative life events. Effective antidepressant therapy reverses this negative emotional bias (NEB) within 1 week. Clinical therapeutic effect usually requires 4–6 weeks. The value of ... -
Premembering Experience: A Hierarchy of Time-Scales for Proactive Attention
(2019-10)Memories are about the past, but they serve the future. Memory research often emphasizes the former aspect: focusing on the functions that re-constitute (re-member) experience and elucidating the various types of memories ... -
Treatment for depression comorbid with dementia
(2019-11)Depression is a common comorbidity in dementia. Randomised controlled studies of antidepressants do not show a significant improvement in depressive symptoms in patients with comorbid dementia and are known to lead to an ... -
Ketamine for suicidal ideation in adults with psychiatric disorders: A systematic review and meta-analysis of treatment trials
(2019-07)Ketamine may reduce suicidal ideation in treatment-resistant depression. But it is not known how quickly this occurs and how long it persists. We undertook a systematic review and meta-analysis to determine the short and ... -
Prevalence of Non-Affective Psychoses in Individuals with Autism Spectrum Disorders: A Systematic Review
(2019-08)Autism spectrum disorders (ASD) and non-affective psychoses such as schizophrenia are commonly acknowledged as discrete entities. Previous research has revealed evidence of high comorbidity between these conditions, but ... -
The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function
(2019)Genome-wide association studies (GWAS) of psychiatric phenotypes have tended to focus on categorical diagnoses, but to understand the biology of mental illness it may be more useful to study traits which cut across traditional ... -
Is adjunctive CBT really effective for schizophrenia?
(2019-09)Although antipsychotic medication remains the mainstay of treatment for schizophrenia, medications alone are not always successful. Cognitive– behavioural therapy (CBT) is recommended as an adjunct to pharmacological ... -
Moderators and mediators of outcome in treatments for anorexia nervosa and bulimia nervosa in adolescents: A systematic review of randomized controlled trials
(2019-09)Objective:To critically appraise papers reporting on moderators and mediators of recommended psychological treatments for anorexia nervosa (AN) and bulimia nervosa (BN) in adolescents. Method:A systematic search of databases ... -
Characteristics of people with pressure ulcers using one year's routinely collected data in a defined diverse community
(2019-09)Objective:To determine if meaningful patient characteristics pertaining to pressure ulcers (PU) can be derived from routinely collected community health data. Methods: A retrospective cohort analysis of records was carried ... -
A Path Signature Approach for Speech Emotion Recognition
(2019-09)Automatic speech emotion recognition (SER) remains a difficult task within human-computer interaction, despite increasing interest in the research community. One key challenge is how to effectively integrate short-term ...
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