Conditions, Lifestyle Factors & Interventions
Recent Submissions
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Blood pressure changes following antihypertensive medication reduction, by drug class and dose chosen for withdrawal: Exploratory analysis of data from the OPTiMISE trial
(2021-02)Aims: Deprescribing of antihypertensive drugs is recommended for some older patients with polypharmacy, but there is little evidence to inform which drug (or dose) should be withdrawn. This study used data from the ... -
An Intuitive Risk Communication Tool to Enhance Patient–Provider Partnership in Diabetes Consultation
(2021-02)Introduction: This technology report introduces an innovative risk communication tool developed to support providers in communicating diabetes-related risks more intuitively to people with type 2 diabetes mellitus ... -
Quantifying the heterogeneity of cognitive functioning in Alzheimer’s disease to extend the placebo-treatment dichotomy: Latent class analysis of individual-participant data from five pivotal randomized clinical trials of donepezil
(2021-02)Background. The extent and profiles of heterogeneity in cognitive functioning among participants in clinical trials of antidementia medication are unknown. We aimed to quantify and identify profiles of heterogeneity of ... -
The use of Fox’s glacier mints to treat ibs-type symptoms in patients with anorexia nervosa in an adult specialist eating disorder unit
(2021-03)Background: Patients with Anorexia Nervosa (AN) often experience Irritable Bowel Syndrome (IBS) type symptoms, including bloating, abdominal pain and acid reflux.(1) Pepper mint oil is used to treat IBS symptoms, due to ... -
Delivering cognitive therapy for adolescent social anxiety disorder in NHS CAMHS: a qualitative analysis of the experiences of young people, their parents and clinicians-in-training
(2021-03)Social anxiety disorder (SAD) is common. It usually starts in adolescence, and without treatment can disrupt key developmental milestones. Existing generic treatments are less effective for young people with SAD than with ... -
Assistive Technology Innovations in Neurological Conditions
(2021-02)Advances in assistive technologies, aimed at maintaining or improving individuals’ function and independence, thereby promoting their well-being [1, 2], have led to improvements in the autonomy and quality of life of ... -
Participatory design to create a VR therapy for psychosis
(2021-02)This paper describes how participatory design was employed in the design of an automated Virtual Reality (VR) psychological therapy (gameChange), putting people with lived experience of psychosis at the heart of the process. ... -
The neurology and neuropsychiatry of COVID-19: a systematic review and meta-analysis of the early literature reveals frequent CNS manifestations and key emerging narratives
(2021-02)There is accumulating evidence of the neurological and neuropsychiatric features of infection with SARS-CoV-2. In this systematic review and meta-analysis, we aimed to describe the characteristics of the early literature ... -
Modelling paralinguistic properties in conversational speech to detect bipolar disorder and borderline personality disorder
(2021-02)Bipolar disorder (BD) and borderline personality disorder (BPD) are two chronic mental health conditions that clinicians find challenging to distinguish based on clinical interviews, due to their overlapping symptoms. In ... -
Individual variation in brain microstructural-cognition relationships in aging
(2021-02)While all individuals are susceptible to age-related cognitive decline, significant inter- and intra-individual variability exists. However, the sources of this variation remain poorly understood. Here, we examined the ... -
“A blank canvas of me”: an interpretive phenomenological analysis study of the experience of client self-disclosure in cognitive behavioural therapy for psychosis
(2021-02)Background: Client disclosure of emotionally salient information to a therapist may be an important factor in the effectiveness of Cognitive Behavioural Therapy for Psychosis (CBTp). The present study explores how people ... -
‘Someone on my level’: A Meta‐Ethnographic Review of Therapeutic Relationships in Cognitive Behavioural Therapy for Psychosis
(2021-02)Objectives: Cognitive Behavioural Therapy for Psychosis (CBTp) demonstratesvariable and at times mild to moderate effect sizes; thus, its therapeutic processesare important to explore. Establishing a secure therapeutic ... -
Mapping brain structural differences and neuroreceptor correlates in Parkinson's disease visual hallucinations: a mega-analysis
(2021-02)Parkinson’s psychosis (PDP) describes a spectrum of symptoms that may arise in Parkinson’s disease (PD) including visual hallucinations (VH). Imaging studies investigating the neural correlates of PDP have been inconsistent ... -
Exploring The Use of Health and Wellbeing Measures During Pregnancy and The First Year Following Birth in Women Living With Pre-Existing Long-Term Conditions: Qualitative Interviews With Women and Healthcare Professionals
(2021-02)Background One way in which care for pregnant and postpartum women living with long-term health conditions (LTCs) may be improved is through the adoption of standardised measures to provide evidence of health outcomes and ... -
Rischio di mortalità con i farmaci antipsicotici nella popolazione psichiatrica anziana? Una revisione sistematica della letteratura
(2016)Scopo dello studio: In Italia, gli anziani raggiungono quasi un quarto della popolazione generale. In questo sottogruppo, gli antipsicotici sono ampiamente prescritti: nonostante siano autorizzati esclusivamente per ... -
Psychosocial interventions in stimulant use disorders: a systematic review and qualitative synthesis of randomized controlled trials
(2018-09)Stimulant use disorders are highly prevalent with a large burden of disease. Most clinical guidelines recommend psychosocial interventions, but there are no clear hierarchies or indications. Moreover, these interventions ... -
Psychosocial interventions in stimulant use disorders: a focus on women
(2017-07)Purpose of review: Stimulant use disorders are significant contributors to the global burden of disease, with a growing impact on women. Psychosocial interventions are the gold standard for treating this condition, but ... -
Is it time to review NICE guidelines on family therapy for anorexia in young people?
(2020-04)Family therapy is recommended by the National Institute for Health and Care Excellence (NICE) for the management of anorexia nervosa in children and young people, but there is limited evidence to back this recommendation. ... -
Can dietary supplements maintain cognition in mid- to late-life?
(2020-12)Cognitive health, and prevention of its decline to dementia, has risen in prominence with a corresponding exploration of modifiable risk factors to prevent a decline in cognitive health with age. This commentary discusses ... -
Can we prevent seasonal affective disorder (SAD) with melatonergic agents?
(2020-06)Seasonal affective disorder (SAD) is a recurrent form of major depression, particularly occurring in the winter months with a generally spontaneous remission in spring/summer. The predictable nature of this condition ...
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