Conditions, Lifestyle Factors & Interventions
Recent Submissions
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A Refugee Rose of competencies and capabilities for mental healthcare of refugees
(2022-02)In this paper, I set out the challenges of care for refugees and suggest approaches to assessment and intervention. I discuss clinical interventions that can address the immediate concern of the clinician in a ... -
The journey of adolescent paranoia: A qualitative study with patients attending child and adolescent mental health services
(2022-02)Objectives: Paranoia is most likely to emerge in adolescence. In adolescents with mental health disorders, the disruptive effect of paranoia on social relationships could worsen outcomes. However, little is known about ... -
The relationship between frequency content and representational dynamics in the decoding of neurophysiological data
(2022-02)Decoding of high temporal resolution, stimulus-evoked neurophysiological data is increasingly used to test theories about how the brain processes information. However, a fundamental relationship between the frequency ... -
Boosting exposure and response prevention with imagery-based techniques: a case study tackling sexual obsessions in an adolescent
(2022-02)Sexual obsessions are common in adolescents with obsessive compulsive disorder (OCD), but how to address these obsessions in a developmentally sensitive manner remains under-explored. This report presents the case of an ... -
Symptom Dynamics and Attention in Depression: Fatigue and Low Positive Affect are Associated With Reduced Orienting Efficiency
(2022-02)Depression is a heterogeneous mental disorder involving a complex interplay between potential etiological and maintenance factors. The current study examined how depression heterogeneity is related to attentional ... -
The psychological journey of weight gain in psychosis
(2022-02)Rapid weight gain is common with antipsychotic medication. Lost confidence, low mood and medication non-adherence often follow. Yet, the dynamic interactions between the physical and psychological consequences of weight ... -
Non-pharamacological treatment for individuals with autism spectrum conditions who display harmful sexual behaviour
(2022-02)Background: Specific treatment and interventions for individuals with Autism Spectrum Conditions who display harmful sexual behaviour have yet to be widely evaluated. This review aims to consolidate and assess the quality ... -
Ketamine for suicidal ideation: New trial challenges current thinking about ketamine
(2022-02)Will ketamine be given to eligible patients with suicidal ideation any time soon? This is hard to say, given the plausible concern that the widespread use of ketamine might trigger a new opioid style crisis.10 Whether ... -
Development and validation of a meta-learner for combining statistical and machine learning prediction models in individuals with depression
(2022-05)The debate of whether machine learning models offer advantages over standard statistical methods when making predictions is ongoing. We discuss the use of a meta-learner model combining both approaches as an alternative. ... -
Generalizing Brain Decoding Across Subjects with Deep Learning
(2022-05)Decoding experimental variables from brain imaging data is gaining popularity, with applications in brain-computer interfaces and the study of neural representations. Decoding is typically subject-specific and does not ... -
Incorporating interventions for unhealthy exercise into eating disorders treatment A survey of attitudes in those with lived experience of an eating disorder
(2022-05)Introduction: There is little consensus on the treatment of unhealthy exercise in eating disorders. Many treatment programmes do not offer any interventions at all. This study explored the attitudes of those with lived ... -
The relationship between short- and long-term memory is preserved across the age range
(2022-06)The aim of the current study was to examine cross-sectionally the changes in the relationship between short- and long-term memory with age. In two experiments, participants across the age-range were tested on contextual-spatial ... -
Personalised treatment for cognitive impairment in dementia: development and validation of an artificial intelligence model
(2022-02)Donepezil, galantamine, rivastigmine and memantine are potentially effective interventions for cognitive impairment in dementia, but the use of these drugs has not been personalised to individual patients yet. We examined ... -
A feasibility study to determine whether the daily consumption of flavonoid-rich pure cocoa has the potential to reduce fatigue and fatigability in people with Parkinson's (pwP)
(2022-01)Summary Flavonoids, plant compounds found in certain foods, may have the ability to improve fatigue and fatigability. However, to date, no well-designed intervention studies assessing the role of flavonoid consumption for ... -
Psychiatric comorbidity and risk of premature mortality and suicide among those with chronic respiratory diseases, cardiovascular diseases, and diabetes in Sweden: A nationwide matched cohort study of over 1 million patients and their unaffected siblings
(2022-01)Persons with noncommunicable diseases have elevated rates of premature mortality. The contribution of psychiatric comorbidity to this is uncertain. We aimed to determine the risks of premature mortality and suicide in ... -
Integrated Enhanced Cognitive Behavioural (I-CBTE) therapy significantly improves effectiveness of inpatient treatment of anorexia nervosa in real life settings
(2022-01)Inpatient treatment of anorexia nervosa (AN) often results in poor outcomes. To address this, the Oxford service has adapted the multistep enhanced cognitive behavioural (CBTE) treatment model, first developed in Italy, ... -
The impact of the COVID-19 pandemic on health service utilisation following selfharm: a systematic review
(2022-01)Background Evidence on the impacts of the pandemic on healthcare presentations for self-harm has accumulated rapidly. However, existing reviews do not include studies published beyond 2020. Aims To systematically review ... -
Psychological mechanisms connected to dissociation: Generating hypotheses using network analyses
(2022-02)A large number of mechanisms, many relating to the processing of affect, have been proposed to cause dissociation. The aim of this study was to use network analyses to identify psychological processes most closely connected ... -
Representation and Outcomes of Individuals With Schizophrenia Seen in Everyday Practice Who Are Ineligible for Randomized Clinical Trials
(2022-02)IMPORTANCE Most evidence about efficacy and safety of antipsychotics in schizophrenia spectrum disorders relies on randomized clinical trials (RCTs). However, owing to their strict eligibility criteria, RCTs represent ... -
Identification of Substrate-specific Allosteric Fingerprints in Matrix Metalloprotease-1 on Amyloid-beta Peptide Aggregates and Drug Screening With Single Molecule Insights
(2022-02)Amyloid-beta peptide (Aβ) is the primary component of water-insoluble extracellular plaques, one of the critical hallmarks of Alzheimer's disease (AD). Matrix metalloproteases (MMPs) are broad-spectrum proteases with ...
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