Browsing by Title
Now showing items 533-552 of 1185
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Improving the rehabilitation of older people after emergency hospital admission
(2018-05)Purpose: Older adults are at risk of functional decline during emergency hospital admissions. This review aims to understand which exercise-based interventions are effective in improving function for older adults who ... -
Improving usability of Electronic Health Records in a UK Mental Health setting: a feasibility study
(2022-06)Electronic Health Records (EHRs) can help clinicians to plan, document and deliver care for patients in healthcare services. When used consistently, EHRs can advance patient safety and quality, and reduce clinician’s ... -
Impulse control disorders in Parkinson disease and RBD
(2019-10)Objective To describe the prevalence, natural history, and risk factors for impulse control behaviors (ICBs) among people with Parkinson disease (PD), those with REM sleep behavior disorder (RBD), and controls. Metho ... -
In Vivo Availability of Cannabinoid 1 Receptor Levels in Patients With First-Episode Psychosis
(2019-07)Importance: Experimental and epidemiological studies implicate the cannabinoid 1 receptor (CB1R) in the pathophysiology of psychosis. However, whether CB1R levels are altered in the early stages of psychosis and whether ... -
In-patient treatment in functional and sectorised care: patient satisfaction and length of stay
(2018-02)Background: Debate exists as to whether functional care, in which different psychiatrists are responsible for in- and out-patient care, leads to better in-patient treatment as compared with sectorised care, in which the ... -
In-vitro diagnostic point-of-care tests in paediatric ambulatory care: A systematic review and meta-analysis
(2020-07)Paediatric consultations form a significant proportion of all consultations in ambulatory care. Point-of-care tests (POCTs) may offer a potential solution to improve clinical outcomes for children by reducing diagnostic ... -
An In-vivo 1H-MRS short-echo time technique at 7T: Quantification of metabolites in Chronic Multiple Sclerosis and Neuromyelitis Optica Brain Lesions and Normal Appearing Brain Tissue
(2021-05)Magnetic Resonance Spectroscopy (MRS) allows for the non-invasive quantification of neurochemicals and has the potential to differentiate between the pathologically distinct diseases, multiple sclerosis (MS) and AQP4Ab-positive ... -
Incidence and outcomes of eating disorders during the COVID-19 pandemic
(2021-07)There are concerns that eating disorders have become commoner during the coronavirus disease 2019 (COVID-19) pandemic. Using the electronic health records of 5.2 million people aged under 30, mostly in the USA, we show ... -
Incidence of Epilepsy and Seizures Over the First 6 Months After a COVID-19 Diagnosis
(2022-11)Background and Objectives The relationship between COVID-19 and epilepsy is uncertain. We studied the potential association between COVID-19 and seizures or epilepsy in the 6 months after infection. Methods We applied ... -
Incidence of neurodegenerative and cerebrovascular diseases associated with antihypertensive drug classes
(2021-01)Antihypertensive drugs (AHTs) are associated with lowered risks of neurodegenerative diseases and stroke. However, the relative risks associated with different AHT classes are unclear. Using an electronic health record ... -
Incidence of Parkinson’s disease, dementia, cerebrovascular disease and stroke in bipolar disorder compared to other psychiatric disorders: An electronic health records network study of 66 million people
(2020-10)Bipolar disorder has been associated with an increased risk for neurodegenerative diseases, but uncertainties remain. The risk relative to other psychiatric disorders is not established. Methods We used a federated ... -
Incidence, co-occurrence, and evolution of long-COVID features: A 6-month retrospective cohort study of 273,618 survivors of COVID-19
(2021-09)Long-COVID refers to a variety of symptoms affecting different organs reported by people following Coronavirus Disease 2019 (COVID-19) infection. To date, there have been no robust estimates of the incidence and co-occurrence ... -
Incidental findings in UK healthy volunteers screened for a COVID-19 vaccine trial
(2022-09)The safety of novel therapeutics and vaccines are typically assessed in early phase clinical trials involving "healthy volunteers." Abnormalities in such individuals can be difficult to interpret and may indicate previously ... -
Incorporating interventions for unhealthy exercise into eating disorders treatment A survey of attitudes in those with lived experience of an eating disorder
(2022-05)Introduction: There is little consensus on the treatment of unhealthy exercise in eating disorders. Many treatment programmes do not offer any interventions at all. This study explored the attitudes of those with lived ... -
Increase in antibiotic prescriptions in out-of-hours primary care in contrast to in-hours primary care prescriptions: service evaluation in a population of 600 000 patients
(2016)Objectives The objective of this study was to describe the frequency and nature of antibiotic prescriptions issued by a primary care out-of-hours (OOH) service and compare time trends in prescriptions between OOH and ... -
Individual variation in brain microstructural-cognition relationships in aging
(2021-02)While all individuals are susceptible to age-related cognitive decline, significant inter- and intra-individual variability exists. However, the sources of this variation remain poorly understood. Here, we examined the ... -
Individuals seeking gender reassignment: marked increase in demand for services
(2018)Aims and method: To describe the pattern of referrals and characteristics of people aged over 18 seeking gender reassignment in Oxfordshire over a 6-year period (2011– 2016). Results: A total of 153 individuals attended ... -
Induced pluripotent stem cells in psychiatry: a critical review
(2021-01)A key challenge in psychiatry research is the development of high-fidelity model systems that can be experimentally manipulated to explore and test pathophysiological mechanisms of illness. In this respect, the emerging ... -
Inducing Affective Learning Biases with Cognitive Training and Prefrontal tDCS: A Proof-of-Concept Study
(2020-10)Cognitive models of mood disorders emphasize a causal role of negative affective biases in depression. Computational work suggests that these biases may stem from a belief that negative events have a higher information ... -
Infant mental health and the role of the health visitor
(2023-09)The theme for June's infant mental health week this year was ‘Bonding before birth’, with organisations sharing the importance of support for parents and carers to enable them to understand baby brain development and how ...