Browsing by Title
Now showing items 458-477 of 1185
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Generalizing Brain Decoding Across Subjects with Deep Learning
(2022-05)Decoding experimental variables from brain imaging data is gaining popularity, with applications in brain-computer interfaces and the study of neural representations. Decoding is typically subject-specific and does not ... -
Generating comparative evidence on new drugs and devices before approval
(2020-03)Fewer than half of new drugs have data on their comparative benefits and harms against existing treatment options at the time of regulatory approval in Europe and the USA. Even when active-comparator trials exist, they ... -
Genetics of self-reported risk-taking behaviour, trans-ethnic consistency and relevance to brain gene expression
(2018)Risk-taking behaviour is an important component of several psychiatric disorders, including attention-deficit hyperactivity disorder, schizophrenia and bipolar disorder. Previously, two genetic loci have been associated ... -
The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function
(2019)Genome-wide association studies (GWAS) of psychiatric phenotypes have tended to focus on categorical diagnoses, but to understand the biology of mental illness it may be more useful to study traits which cut across traditional ... -
Getting Better: How Well Are We Assessing and Managing Anxiety Disorders in Community Camhs?
(2023-07)Anxiety disorders are a common presenting problem for young people under the care of Melksham Community CAMHS. Guidelines from NICE outline recommendations for best practice in assessment and treatment of these disorders. ... -
Global perspectives on under‐funding for Clinical Research Training Fellowships in Nursing
(2021-03)The impact of nursing research is well described in the literature and nurses have a long‐standing track record in delivering high‐quality clinical research that adds value and improves patient care and outcomes (Ferguson ... -
Global prevalence and risk factors for mental health problems in police personnel: a systematic review and meta-analysis
(2020-05)Police face an increased risk of developing mental health problems, yet reliable estimates of their psychological difficulties remain unknown. This systematic review and meta-analysis estimate the pooled prevalence and ... -
Glucocorticoid ultradian rhythmicity differentially regulates mood and resting state networks in the human brain: A randomised controlled clinical trial
(2021-02)Adrenal glucocorticoid secretion into the systematic circulation is characterised by a complex rhythm, composed of the diurnal variation, formed by changes in pulse amplitude of an underlying ultradian rhythm of short ... -
Grey matter microstructural differencesin developmental stuttering
(2021-03)Theoretical accounts of developmental stuttering implicate dysfunctional cortico-striatal-thalamo-cortical motor loops through the putamen, but empirical evidence of these proposed differences is currently limited. ... -
GRIN2A (NR2A): a gene contributing to glutamatergic involvement in schizophrenia
(2023-09)Involvement of the glutamate system, particularly N-methyl-D-aspartate (NMDA) receptor hypofunction, has long been postulated to be part of the pathophysiology of schizophrenia. An important development is provided by ... -
Guided, internet based, cognitive behavioural therapy for post-traumatic stress disorder: pragmatic, multicentre, randomised controlled non-inferiority trial (RAPID)
(2022-06)Objective To determine if guided internet based cognitive behavioural therapy with a trauma focus (CBT-TF) is non-inferior to individual face-to-face CBT-TF for mild to moderate post-traumatic stress disorder (PTSD) to one ... -
Happenstance and regulatory culture: the evolution of innovative community mental health services in Oxfordshire in the late twentieth century
(2022-12)This paper uses co-produced historical material to explore the evolution of two innovative mental healthcare institutions that emerged in Oxfordshire in the 1960s. We highlight how the trajectories of both institutions ... -
Harnessing mobile devices to support the delivery of community-based clinical care: a participatory evaluation
(2019)Background:A large provider of community health services (an NHS Trust in England) deployed Apple iPads to its front-line community-based healthcare clinicians (predominantly nurses) to enable them to increase responsiveness ... -
Harnessing the nursing contribution to COVID-19 mass vaccination programmes: Addressing hesitancy and promoting confidence
(2021-04)The need for a mass vaccination programme for COVID-19 is considered a pivotal public health strategy to reduce rates of infection, hospitalizations and deaths which have been so much a feature of the past year of the ... -
Having a son or daughter with an intellectual disability transition to adulthood: A parental perspective
(2020-04)Background: Transition to adulthood is an important time for young people and may be a particularly challenging time for people with intellectual disabilities. However, there has been little research in the UK regarding ... -
Health Outcome Prioritization in Alzheimer's Disease: Understanding the Ethical Landscape.
(2020-07)BACKGROUND:Dementia has been described as the greatest global health challenge in the 21st century on account of longevity gains increasing its incidence, escalating health and social care pressures. These pressures highlight ... -
Health promotion for vitamin use in children under 5 years
(2023-11)There is an increasing understanding of the importance of vitamins and minerals for the health and development of the population. Bethany Boddy looks at the evidence base for health promotion in children under the age of 5 years -
The heartland of psychiatry, revisited
(2019-11)The role of doctors will undoubtedly evolve as knowledge, and perverse ignorance become more universally available to all via the internet. The role of the psychiatrist must be to relate real advances in understanding ... -
Hebephrenia is dead, long live hebephrenia, or why Hecker and Chaslin were on to something
(2019-05-03)Since its first description in 1863, ‘hebephrenia’ has highlighted a group of patients characterised by an early onset of illness, formal thought disorder, bizarre behaviour and incongruent emotional expression. A proportion ... -
Helping young people who self-harm
(2017-02)Key learning points: For many young people, the function of self-harm is to escape an unbearable emotional state; relief and negative feelings experienced following self-harm can result in a cycle of self-harming behaviour; ...