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Now showing items 17-36 of 1185
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Actigraphic patterns, impulsivity and moodinstability in bipolar disorder, borderlinepersonality disorder and healthy controls.
(2020-01)Objectives:To differentiate the relation between the structure and timing of rest-activity patterns and symptoms of impulsivity and mood instability in bipolar disorder (BD), borderline personality disorder(BPD) and healthy ... -
Actigraphy-derived physical activity levels and circadian rhythm parameters in patients with psoriatic arthritis: relationship with disease activity, mood, age and BMI
(2023-07)Background: Psoriatic arthritis (PsA) is associated with sleep disturbance, depression and a lifetime risk of obesity and cardiovascular disease. To date, there have been no studies investigating the relationship between ... -
Active Support and “meaningful activity.” What is the meaning of “meaningful”?
(2021-09)Active Support is an approach that aims to engage people in meaningful activities. It is one of the best evidenced models of support for adults with learning disabilities (Mansell and Beadle-Brown, 2012). Adults using ... -
Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization
(2023-08)Post-COVID cognitive deficits, including 'brain fog', are clinically complex, with both objective and subjective components. They are common and debilitating, and can affect the ability to work, yet their biological ... -
Acute mental health nurses’ experience of forcibly touching service users during physical restraint
(2020-10)Mental health nurses use forcible touch during physical restraint. Little research considers nurses’ experiences and the meanings they give to forcible touch. This study investigated nurses’ lived experiences of forcibly ... -
Acute neural effects of fluoxetine on emotional regulation in depressed adolescents
(2022-05)Adolescent major depressive disorder (MDD) is associated with disrupted processing of emotional stimuli and difficulties in cognitive reappraisal. Little is known however about how current pharmacotherapies act to modulate ... -
Adapted CBT to Stabilize Sleep on Psychiatric Wards: a Transdiagnostic Treatment Approach
(2018-04-04)Background: Almost all patients admitted at acute crisis to a psychiatric ward experience clinically significant symptoms of insomnia. Ward environments pose challenges to both sleep and the delivery of therapy. Despite ... -
Adapted problem adaptation therapy for depression in mild to moderate Alzheimer's disease dementia: A randomized controlled trial
(2024-03)Introduction: Trials of effectiveness of treatment options for depression in dementia are an important priority. Methods: Randomized controlled trial to assess adapted Problem Adaptation Therapy (PATH) for depression in ... -
Adapting cognitive behavioural therapy for adolescents with psychosis: insights from the Managing Adolescent first episode in psychosis study (MAPS)
(2022-01)Background: Onset of psychosis commonly occurs in adolescence, and long-term prognosis can be poor. There is growing evidence, largely from adult cohorts, that Cognitive Behavioural Therapy for Psychosis (CBTp) and ... -
Adaptive learning from outcome contingencies in eating-disorder risk groups
(2022-07)Eating disorders are characterised by altered eating patterns alongside overvaluation of body weight or shape, and have relatively low rates of successful treatment and recovery. Notably, cognitive inflexibility has been ... -
Adding value, reducing research waste, the role of the NHS research and development management community
(2018-02-23)Purpose – Research suggests that 85 per cent of health research is avoidably wasted. The research and development management community has an important role in the research process and can contribute to improving the ... -
Addressing concerns about smoking cessation and mental health: theoretical review and practical guide for healthcare professionals
(2020-07)Smoking rates in people with depression and anxiety are twice as high as in the general population, even though people with depression and anxiety are motivated to stop smoking. Most healthcare professionals are aware that ... -
Adjunctive Psychotherapy for Bipolar Disorder A Systematic Review and Component Network Meta-analysis
(2020-10)Importance Several psychotherapy protocols have been evaluated as adjuncts to pharmacotherapy for patients with bipolar disorder, but little is known about their comparative effectiveness. Objective To use systematic ... -
Advance care planning in patients referred to hospital for acute medical care
(2020-02)Advance care planning (ACP) is a voluntary process of discussion about future care between an individual and their care provider. ACP is a key focus of national policy as a means to improve patient centered care at the ... -
Advances in digital CBT: where are we now, and where next?
(2022-10)Digital CBT refers to the use of digital tools, platforms or devices to deliver or enhance cognitive behavioural therapy assessment, formulation, treatment, training and supervision. The ‘Advances in Digital CBT’ special ... -
Advances in the computational understanding of mental illness
(2020-07)Computational psychiatry is a rapidly growing field attempting to translate advances in computational neuroscience and machine learning into improved outcomes for patients suffering from mental illness. It encompasses both ... -
Affective bias as a rational response to the statistics of rewards and punishments
(2017-10)Affective bias, the tendency to differentially prioritise the processing of negative relative to positive events, is commonly observed in clinical and non-clinical populations. However, why such biases develop is not known. ... -
The Africa Ethics Working Group (AEWG): a model of collaboration for psychiatric genomic research in Africa [version 1; peer review: awaiting peer review]
(2021-07)The Africa Ethics Working Group (AEWG) is a South-South-North collaboration of bioethics and mental health researchers from sub-Saharan Africa, working to tackle emerging ethical challenges in global mental health research. ... -
Age-related response speed deficits arise from specific impairments in sensory evidence accumulation rate
(2021-11)Older adults exposed to enriched environments (EE) maintain relatively higher levels of cognitive function, even in the face of compromised markers of brain health. Response speed (RS) is often used as a simple proxy to ... -
Agoraphobic avoidance in patients with psychosis: Severity and response to automated VR therapy in a secondary analysis of a randomised controlled clinical trial
(2022-11)Background: The social withdrawal of many patients with psychosis can be conceptualised as agoraphobic avoidance due to a range of long-standing fears. We hypothesised that greater severity of agoraphobic avoidance is ...