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Now showing items 1159-1178 of 1185
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What is the clinical value of mHealth for patients?
(2020-01)Despite growing interest from both patients and healthcare providers, there is little clinical guidance on how mobile apps should be utilized to add value to patient care. We categorize apps according to their functionality ... -
What is the evidence for using bed rest as part of hospital treatment of severe anorexia nervosa?
(2019-04)Bed rest is commonly used on medical and paediatric wards as part of nursing management of the physically compromised patient with severe anorexia nervosa. The aim of this study was to review the evidence base of bed rest ... -
What is the relationship between dissociation and self-harming behaviour in adolescents?
(2019-01)Deliberate self‐harm in adolescents is an increasing clinical problem, but there is a limited understanding of the mechanisms causing or maintaining this behaviour. One proposed mechanism is that of dissociation. However, ... -
What is the return on investment for laboratory medicine? The antidote to silo budgeting in diagnostics
(2020-06)Procuring and managing diagnostic services, such as laboratory medicine, is generally based on cost and activity. Improving productivity of laboratory services therefore tends to focus on reducing the cost per test. However, ... -
What proportion of patients at the end of life contact out-of-hours primary care? A data linkage study in Oxfordshire
(2018-04)Objectives: Out-of-hours (OOH) primary care services are a key element of community care at the end of life, yet there have been no previous attempts to describe the scope of this activity. We aimed to establish the ... -
What we learn about bipolar disorder from large-scaleneuroimaging: Findings and future directions from theENIGMA Bipolar Disorder Working Group
(2020-06)MRI-derived brain measures offer a link between genes, the environment and behav-ior and have been widely studied in bipolar disorder (BD). However, many neuroimag-ing studies of BD have been underpowered, leading to varied ... -
The WHELD programme: showing the benefits
(2019-01)The WHELD study demonstrates that with support home care teams can incorporate into practice a focused approach to person centred care, augmented with other therapeutic elements of personalised social activities and ... -
When Deploying Predictive Algorithms, Are Summary Performance Measures Sufficient?
(2020-01)The last decade’s growth in artificial intelligence, machine learning, and statistical methods for high-dimensional data has driven a zeitgeist of prediction (or forecasting) in medicine and psychiatry. Algorithms for ... -
When Helping is Risky: Behavioral and Neurobiological Mechanisms of Prosocial Decisions Entailing Risk.
(2020-03)Helping others can entail risks. Doctors that treat infectious patients may risk their own health, intervening in a fight can lead to injury, and organ donations can lead to medical complications. When helping others comes ... -
When Natural Behavior Engages Working Memory
(2020-12)Working memory (WM) enables temporary storage and manipulation of information,1 supporting tasks that require bridging between perception and subsequent behavior. Its properties, such as its capacity, have been thoroughly ... -
Where Is the Value of Laboratory Medicine and How Do You Unlock It?
(2020-09)The innovation pathway by which a newly discovered biomarker is developed into a medical test and used in routine clinical practice comprises a number of different processes split between 2 phases. The first follows on ... -
Which Dopamine Polymorphisms are Functional? Systematic Review and Meta-Analysis of COMT, DAT, DBH, DDC, DRD1-5, MAOA, MAOB, TH, VMAT1 and VMAT2
(2019-05)BACKGROUND: Many polymorphisms in dopamine genes are reported to affect cognitive, imaging or clinical phenotypes. It is often inferred or assumed that such associations are causal, mediated by a direct effect of the ... -
Whole-brain white matter organization, intelligence, and educational attainment
(2019-03)General cognitive ability, sometimes referred to as intelligence, is associated with educational attainment throughout childhood. Most studies that have explored the neural correlates of intelligence in childhood focus ... -
Why do ambulance employees (not) seek organisational help for mental health support? A mixed-methods systematic review protocol of organisational support available and barriers/facilitators to uptake
(2022-10)Introduction The COVID-19 pandemic is exacerbating a wide range of symptoms of poor mental health among emergency medical service (EMS) ambulance populations. Evidence suggests that using organisational support can improve ... -
Why do patients with psychosis listen to and believe derogatory and threatening voices? 2 21 reasons given by patients
(2020-05)Background: Around two thirds of patients with auditory hallucinations experience derogatory 37 and threatening voices (DTVs). Understandably, when these voices are believed then common 38 consequences can be depression, ... -
Why Health Care Professionals Belong to an Intensive Care Virtual Community: Qualitative Study
(2019-11)Background: Clinical practice variation that results in poor patient outcomes remains a pressing problem for health care organizations. Some evidence suggests that a key factor may be ineffective internal and professional ... -
Why is COVID-19 associated with mental illness?
(2021-08)The COVID-19 pandemic has taken a toll on people’s mental health. Besides the indirect impact of the pandemic, a diagnosis of COVID 19 is itself associated with a greater risk of subsequent mental illness. Conversely, ... -
Why sleep matters for young people who may get depressed
(2020-04)Depression and anxiety are negative emotional states familiar to us all through personal experience. Less familiar are severe states of depression, in particular, which can actually shorten the lives of sufferers by over ... -
Will COVID-19 be the coming of age for point-of-care testing?
(2020-09)BACKGROUND As countries deal with the COVID-19 pandemic in varying ways, one area of agreement is the need to test for the COVID-19 virus in as many people as possible. Beeching et al have rightly pointed out that ... -
Withdrawal, dependence and adverse events of antidepressants: lessons from patients and data
(2019-10)Editorial.