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Now showing items 592-611 of 1185
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The journey of adolescent paranoia: A qualitative study with patients attending child and adolescent mental health services
(2022-02)Objectives: Paranoia is most likely to emerge in adolescence. In adolescents with mental health disorders, the disruptive effect of paranoia on social relationships could worsen outcomes. However, little is known about ... -
Kalirin as a Novel Treatment Target for Cognitive Dysfunction in Schizophrenia
(2021-12)The cognitive dysfunction experienced by patients with schizophrenia represents a major unmet clinical need. We believe that enhancing synaptic function and plasticity by targeting kalirin may provide a novel means to ... -
Ketamine for Psychiatric Disorders
(2019-07)This new edition of The ECT Handbook comes six years after the publication of the 3rd edition. In the intervening period there have been no major changes in the practice of electroconvulsive therapy, but continuing research ... -
Ketamine for suicidal ideation in adults with psychiatric disorders: A systematic review and meta-analysis of treatment trials
(2019-07)Ketamine may reduce suicidal ideation in treatment-resistant depression. But it is not known how quickly this occurs and how long it persists. We undertook a systematic review and meta-analysis to determine the short and ... -
Ketamine for suicidal ideation: New trial challenges current thinking about ketamine
(2022-02)Will ketamine be given to eligible patients with suicidal ideation any time soon? This is hard to say, given the plausible concern that the widespread use of ketamine might trigger a new opioid style crisis.10 Whether ... -
Ketamine treatment for depression: qualitative study exploring patient views
(2021-01)Ketamine is a new and promising treatment for depression but comes with challenges to implement because of its potential for abuse. Aims We sought the views of patients to inform policy and practical decisions about ... -
The Kilim plot: A tool for visualizing network meta‐analysis results for multiple outcomes
(2020-06)Network meta‐analysis (NMA) can be used to compare multiple competing treatments for the same disease. In practice, usually a range of outcomes is of interest. As the number of outcomes increases, summarizing results from ... -
Knowledge and Use of Novel Psychoactive Substances in Italy: a Survey-Based Study in the General Population
(2021-11)In this study, we aimed to identify the current trend of novel psychoactive substance (NPS) consumption in Italy and the level of knowledge about NPS in the general population and to explore the presence of risk factors ... -
The knowns and unknowns of SSRI treatment in young people with depression and anxiety: efficacy, predictors, and mechanisms of action
(2021-08)The use of SSRIs for the treatment of depression and anxiety in young people is increasing. However, the effects of SSRIs in adolescence, a time when there are substantial changes in neural, cognitive, and social functioning, ... -
A leaky umbrella has little value: evidence clearly indicates the serotonin system is implicated in depression
(2023-06)A recent “umbrella” review examined various biomarkers relating to the serotonin system, and concluded there was no consistent evidence implicating serotonin in the pathophysiology of depression. We present reasons for why ... -
Learning from nursing students’ experiences and perceptions of their clinical placements in nursing homes: An integrative literature review
(2021-05)Objectives This paper aims to investigate pre-registration nursing students' experiences and perceptions of their clinical placements in nursing homes in order to develop recommendations for nurse educators. Evidence ... -
Learning from school nursing practices and new ways of working during the COVID-19 pandemic: A qualitative study
(2023-05)Aims: To explore school nurses' experiences during the COVID-19 pandemic, focusing on: methods enabling service delivery, factors affecting school nurses' ability to support children, work with the interdisciplinary team, ... -
Learning to Detect Bipolar Disorder and Borderline Personality Disorder with Language and Speech in Non-Clinical Interviews
(2020-08)Bipolar disorder (BD) and borderline personality disorder (BPD) are both chronic psychiatric disorders. However, their overlapping symptoms and common comorbidity make it challenging for the clinicians to distinguish ... -
Learning to optimize perceptual decisions through suppressive interactions in the human brain
(2019-01)Translating noisy sensory signals to perceptual decisions is critical for successful interactions in complex environments. Learning is known to improve perceptual judgments by filtering external noise and task-irrelevant ... -
Learning to optimize perceptual decisions through suppressive interactions in the human brain
(2019-01)Translating noisy sensory signals to perceptual decisions is critical for successful interactions in complex environments. Learning is known to improve perceptual judgments by filtering external noise and task-irrelevant ... -
Legal capacity and the right to decide: WHO QualityRights core training: mental health and social services: course guide
(2019)Ensuring mental health and well-being has become a worldwide imperative and an important target of the Sustainable Development Goals. But in all countries around the world, our response has been woefully insufficient, and ... -
Length of hospitalisation for people with severe mental illness: is the longer the better? Commentary on… Cochrane Corner
(2021)The Cochrane review in this month’s Cochrane Corner (Babalola 2014) compares short-stay hospital admission to long-stay/standard admission in patients with severe mental illness for a number of outcomes in a total 2030 ... -
A life more ordinary: A peer research method qualitative study of the Feeling Safe Programme for persecutory delusions
(2022-07)Background: The Feeling Safe Programme is a cognitive therapy developed to improve outcomes for individuals with persecutory delusions. It is theoretically driven, modular and personalised, with differences in ... -
Life problems in children and adolescents who self-harm: findings from the multicentre study of self-harm in England
(2022-01)Background: Self-harm, a significant and increasing global problem in children and adolescents, is often repeated and is associated with risk of future suicide. To identify potential interventions, we need to understand ... -
Lighthouse Parenting Programme: Description and pilot evaluation of Mentalization-Based Treatment (MBT) to address child maltreatment.
(2018)This paper introduces an innovative Mentalization - Based Treatment (MBT) parenting intervention for families where children are at risk of maltreatment. The Lighthouse MBT Parenting Programme aims to prevent child ...