Browsing Mental Disorders (General) by Title
Now showing items 21-40 of 47
-
The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function
(2019)Genome-wide association studies (GWAS) of psychiatric phenotypes have tended to focus on categorical diagnoses, but to understand the biology of mental illness it may be more useful to study traits which cut across traditional ... -
Identifying psychiatric diagnosis from missing mood data through the use of log-signature features
(2022-11)The availability of mobile technologies has enabled the efficient collection of prospective longitudinal, ecologically valid self-reported clinical questionnaires from people with psychiatric diagnoses. These data streams ... -
Impact of the COVID-19 Pandemic on the Global Delivery of Mental Health Services and Telemental Health: Systematic Review
(2022-08)The COVID-19 pandemic required mental health services around the world to adapt quickly to the new restrictions and regulations put in place to reduce the risk of transmission. As face-to-face contact became difficult, ... -
Induced pluripotent stem cells in psychiatry: a critical review
(2021-01)A key challenge in psychiatry research is the development of high-fidelity model systems that can be experimentally manipulated to explore and test pathophysiological mechanisms of illness. In this respect, the emerging ... -
Magnitude and variability of structural brain abnormalities in neuropsychiatric disease: protocol for a network meta-analysis of MRI studies
(2021-04)Introduction Structural MRI is the most frequently used method to investigate brain volume alterations in neuropsychiatric disease. Previous meta-analyses have typically focused on a single diagnosis, thereby precluding ... -
Mental health responses in countries hosting refugees from Ukraine
(2022-04)The Ukrainian refugee crisis highlights the many issues associated with trauma, distress, mental and physical health, culturally competent assessments, and meaningful support and interventions. This crisis requires ... -
A narrative review of ablative neurosurgery in refractory mental disorders
(2022-07)Neurosurgery for mental disorder (NMD) is currently performed in the UK for cases of severe depressive disorder and obsessive–compulsive disorder refractory to treatment, under stringent regulations as set out under the ... -
The neurology and neuropsychiatry of COVID-19: a systematic review and meta-analysis of the early literature reveals frequent CNS manifestations and key emerging narratives
(2021-02)There is accumulating evidence of the neurological and neuropsychiatric features of infection with SARS-CoV-2. In this systematic review and meta-analysis, we aimed to describe the characteristics of the early literature ... -
Onset and recurrence of psychiatric disorders associated with anti-hypertensive drug classes
(2021-05)The major anti-hypertensive (AHT) drug classes have been associated with differential risks of psychiatric disorders. However, existing data are limited largely to depression, and confounding variables have not always been ... -
Overlap in genetic risk for cross-disorder vulnerability to mental disorders and genetic risk for altered subcortical brain volumes
(2021-01)Background: There have been considerable recent advances in understanding the genetic architecture of psychiatric disorders as well as the underlying neurocircuitry. However, there is little work on the concordance of genetic ... -
The Oxford study of Calcium channel Antagonism, Cognition, Mood instability and Sleep (OxCaMS): study protocol for a randomised controlled, experimental medicine study
(2019-02)Background: The discovery that voltage-gated calcium channel genes such as CACNA1C are part of the aetiology of psychiatric disorders has rekindled interest in the therapeutic potential of L-type calcium channel (LTCC) ... -
Promoting the sexual health of people living with severe mental illness
(2020-08)Sexual health is an important part of an individual’s overall health profile. However, for people with a severe mental illness (SMI), maintaining optimal sexual health can be a challenge. Mental health nurses have an ... -
A Refugee Rose of competencies and capabilities for mental healthcare of refugees
(2022-02)In this paper, I set out the challenges of care for refugees and suggest approaches to assessment and intervention. I discuss clinical interventions that can address the immediate concern of the clinician in a ... -
Safety of 80 antidepressants, antipsychotics, anti-attention-deficit/ hyperactivity medications and mood stabilizers in children and adolescents with psychiatric disorders: a large scale systematic meta-review of 78 adverse effects
(2020-06)Mental disorders frequently begin in childhood or adolescence. Psychotropic medications have various indications for the treatment of mental disorders in this age group and are used not infrequently off‐label. However, ... -
Six-month Neurological and Psychiatric Outcomes in 236,379 Survivors of COVID-19
(2021-01)Background. Neurological and psychiatric sequelae of COVID-19 have been reported, but there are limited data on incidence rates and relative risks. Methods. Using retrospective cohort studies and time-to-event analysis, ... -
Supported decision making for people with mental health disorders in clinical practice: a systematic review.
(2019-10)Objectives: The Convention on the Rights of Persons with Disabilities (CRPD) was adopted at the United Nations Assembly in 2006. The main aim of the convention is to ensure equal rights for people with disabilities including ... -
Supporting people in mental health crisis in 21st-century Britain
(2020-02)Recent years have seen a surge in interest in mental healthcare and some reduction in stigma. Partly as a result of this, alongside a growing population and higher levels of societal distress, many more people are ... -
The Systemic Assessment Clinic, a Novel Method for Assessing Patients in General Adult Psychiatry: Presentation and Preliminary Service Evaluation.
(2020-08)The traditional model of psychiatric assessment and diagnosis can be criticised as reductive. We developed an innovative model for psychiatric assessment of adult patients referred to our adult mental health team, the ... -
Time to focus more on promoting mental health than treating mental illness
(2018-03)Mental health problems are a major contributor to overall burden of disease worldwide. In UK, it represents up to 23% of the total burden of disease - the largest single cause of disability. To build a healthier, more ... -
The times they are a-changin’
(2018-07)Editorial: "The first issue of Evidence-Based Mental Health (EBMH) is celebrating the 20th anniversary. Readers were welcomed to EBMH in 1998, which was designed to assist ‘mental health clinicians stay up to date with the ...
