Browsing Mental Disorders (General) by Title

Ultradian hydrocortisone replacement alters neuronal processing, emotional ambiguity, affect and fatigue in adrenal insufficiency: The PULSES trial

Harmer, Catherine J (2023-10)

Background: Primary adrenal insufficiency (PAI) mortality and morbidity remain unacceptably high, possibly arising as glucocorticoid replacement does not replicate natural physiology. A pulsatile subcutaneous pump can ...

Understanding agoraphobic avoidance: the development of the Oxford Cognitions and Defences Questionnaire (O-CDQ)

Rosebrock, Laina; Lambe, Sinead; Mulhall, Sophie; Petit, Ariane; Saidel, Simone; Mitchell, Joanna; Clark, David M; Waite, Felicity; Freeman, Daniel (2022-02)

Many patients with mental health disorders become increasingly isolated at home due to anxiety about going outside. A cognitive perspective on this difficulty is that threat cognitions lead to the safety-seeking behavioural ...

Unraveling Mechanisms of Patient-Specific NRXN1 Mutations in Neuropsychiatric Diseases Using Human Induced Pluripotent Stem Cells

Tunbridge, Elizabeth (2020-03)

Rare heterozygous deletions in the neurexin 1 (NRXN1) gene robustly increase an individual's risk of developing neurological and psychiatric disorders. However, the molecular bases by which different mutations result in ...

Variation in spend on young mental health across Clinical Commissioning Groups in England: a cross-sectional observational study

External author(s) only (2019-08)

Objectives To investigate whether the rate of spend on child and adolescent mental health is influenced by demand for other competing services in local commissioning decisions. Design Analysis of spend data by Clinical ...

What can siblings and cousins tell us about the role of early life family income in the aetiologies of violent crime, substance misuse and psychiatric morbidity?

Fazel, Seena (2022-03)

In our recent paper,1 we examined associations between family income during childhood and adolescence on subsequent risks of developing psychiatric disorders, having substance misuse problems and being arrested for a violent ...