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Now showing items 81-88 of 88
Predicting motor, cognitive & functional impairment in Parkinson’s
(2019-07)
Objective: We recently demonstrated that 998 features derived from a simple 7-minute smartphone test could distinguish between controls, people with Parkinson’s and people with idiopathic Rapid Eye Movement sleep behavior ...
New Approaches in Hypertension Management: a Review of Current and Developing Technologies and Their Potential Impact on Hypertension Care
(2019-06)
Hypertension is a key risk factor for cardiovascular disease. Currently, around a third of people with hypertension are undiagnosed, and of those diagnosed, around half are not taking antihypertensive medications. The World ...
Development of a core outcome set for lower limb orthopaedic surgical interventions in ambulant children and young people with cerebral palsy: a study protocol
(2020-03)
Introduction
Musculoskeletal deformities and gait deviations are common features in ambulatory cerebral palsy (CP). Deformity correction through lower limb orthopaedic surgery is the standard form of care aimed at improving ...
Cognitive Performance, Quality and Quantity of Movement Reflect Psychological Symptoms in Adolescents
(2020-05)
The presentation of unhealthy psychological symptoms are rising
sharply in adolescents. Detrimental lifestyle behaviours are proposed
as both possible causes and consequences. This study set
out to compare selected ...
Molecular and antibody point-of-care tests to support the screening, diagnosis and monitoring of COVID-19
(2020-04)
Moving diagnostic testing for COVID-19 from laboratory settings to the point of care is potentially transformative in the rate and quantity of testing that could be performed. Eleven diagnostic tests that are potentially ...
Identification of Substrate-specific Allosteric Fingerprints in Matrix Metalloprotease-1 on Amyloid-beta Peptide Aggregates and Drug Screening With Single Molecule Insights
(2022-02)
Amyloid-beta peptide (Aβ) is the primary component of water-insoluble extracellular plaques, one of the
critical hallmarks of Alzheimer's disease (AD). Matrix metalloproteases (MMPs) are broad-spectrum
proteases with ...
Women’s information needs around urine testing for urinary tract infections: a qualitative study
(2022-02)
Background Urinary tract infection (UTI) is one of the commonest bacterial infections in general practice, with urine testing a frequent feature of its management. Urinary dipsticks are widely used, with urine culture the ...
Assessing Fluid Resuscitation in Adults with Sepsis Who Are Not Mechanically Ventilated: a Systematic Review of Diagnostic Test Accuracy Studies
(2019-05)
BACKGROUND: Fluid resuscitation is a widely used intervention
that is mandated in the management of sepsis.
While its use can be life-saving, its overuse is associated
with harm. Despite this, the best means of assessing ...