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Patterns in Weight and Physical Activity Tracking Data Preceding a Stop in Weight Monitoring: Observational Analysis
(2020-03)
Background: Self-regulation for weight loss requires regular self-monitoring of weight, but the frequency of weight tracking commonly declines over time.
Objective: This study aimed to investigate whether it is a decline ...
Effective psychological treatment for PTSD changes the dynamics of specific large-‐scale brain networks
(2020-01)
Very
little
is
known
about
the
role
of
effective
cognitive
therapy
in
reversing
imbalances
in
brain
activity
after
trauma.
We
hypothesised
that
exaggerated
threat
perception
characteristic
of
p ...
Pharmacological Treatments for Social Anxiety Disorder in Adults: A Systematic Review and Network Meta-Analysis
(2020-02)
Objective: The aim of this paper was to provide a systematic review and update on the pharmacotherapy of social anxiety disorder (SAD), including the efficacy and tolerability of these agents, the ranking of interventions, ...
Five models for child and adolescent data linkage in the UK: a review of existing and proposed methods
(2020-02)
Over the last decade dramatic advances have been made
in both the technology and data available to better
understand the multifactorial influences on child and
adolescent health and development. This paper seeks
to ...
Unraveling Mechanisms of Patient-Specific NRXN1 Mutations in Neuropsychiatric Diseases Using Human Induced Pluripotent Stem Cells
(2020-03)
Rare heterozygous deletions in the neurexin 1 (NRXN1) gene robustly increase an individual's risk of developing neurological and psychiatric disorders. However, the molecular bases by which different mutations result in ...
What does COVID mean for UK mental health care?
(2020-06)
The coronavirus disease (COVID) pandemic is the biggest disaster United Kingdom has seen for many decades. Not since World War II has there been such risk, displacement and change affecting the whole community. This is the ...
A single administration of ‘microbial’ D-alanine to healthy volunteers augments reaction to negative emotions: a comparison with D-serine
(2020-03)
Background Activation of the glutamate N-methyl-D-Aspartate receptor (NMDAR) with its co-agonist D-serine has been shown to improve subjective mood in healthy volunteers. D-alanine is another potent NMDAR co-agonist which ...
Factors associated with fatigue in CNS inflammatory diseases with AQP4 and MOG antibodies
(2020-02)
Objective: Fatigue is a common and disabling symptom amongst people withmultiple sclerosis, however it has not been compared across the central nervoussystem (CNS) inflammatory diseases associated with aquaporin-4 (AQP4) ...
Addressing concerns about smoking cessation and mental health: theoretical review and practical guide for healthcare professionals
(2020-07)
Smoking rates in people with depression and anxiety are twice as high as in the general population, even though people with depression and anxiety are motivated to stop smoking. Most healthcare professionals are aware that ...
COVID-19, mental health and ethnic minorities
(2020-07)
There is little formal guidance
for the busy clinician in balancing
different risks for individual mental health
patients and treating appropriately. To fill this gap, we propose three core
actions that may help:
1. ...