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Now showing items 11-20 of 158
Examination of the neural basis of psychotic-like experiences in adolescence during processing of emotional faces
(2020-03)
Contemporary theories propose that dysregulation of emotional perception is involved in the aetiology of psychosis. 298 healthy adolescents were assessed at age 14- and 19-years using fMRI while performing a facial emotion ...
Development of the Ketamine Side Effect Tool
(2020-04)
Background: Currently, no specific, systematic assessment tool for the monitoring and reporting of ketamine-related side effects exists. Our aim was to develop a comprehensive Ketamine Side Effect Tool (KSET) to capture ...
Pharmacological interventions for self-harm in adults (Protocol)
(2020-07)
This is a protocol for a Cochrane Review (intervention). The objectives are as follows:
To assess the effects of psychosocial or pharmacological interventions for self‐harm (SH) compared to comparison types of care (e.g. ...
Does repeatedly viewing overweight versus underweight images change perception of and satisfaction with own body size?
(2020-04)
Body dissatisfaction is associated with subsequent eating disorders and weight gain. One-off exposure to bodies of different sizes changes perception of others' bodies, and perception of and satisfaction with own body size. ...
Methotrexate and relative risk of dementia amongst patients with rheumatoid arthritis: a multi-national multi-database case-control study
(2020-04)
Background
Inflammatory processes have been shown to play a role in dementia. To understand this role, we selected two anti-inflammatory drugs (methotrexate and sulfasalazine) to study their association with dementia ...
Real-world effect of antidepressants for depressive disorder in primary care: protocol of a population-based cohort study
(2020-06)
Introduction Clinical guidelines recommend antidepressants as the first line of treatment for adults with moderate-to-severe depression. Randomised trials provide the best evidence on the comparative effectiveness of ...
Cognitive neuropsychological theory of antidepressant action: a modern-day approach to depression and its treatment
(2020-01)
Depression is a leading cause of disability worldwide and improving its treatment is a core research priority for future programmes. A change in the view of psychological and biological processes, from seeing them as ...
Deriving information from missing data: implications for mood prediction
(2020-06)
The availability of mobile technologies has enabled the efficient collection prospective longitudinal,
ecologically valid self-reported mood data from psychiatric patients. These data streams have potential
for improving ...
A randomised controlled trial of therapist-assisted online psychological therapies for posttraumatic stress disorder (STOP-PTSD): trial protocol
(2020-04)
Background: Over the last few decades, effective psychological treatments for posttraumatic stress disorder (PTSD) have been developed, but many patients are currently unable to access these treatments. There is initial ...
Subjective cognitive complaints given in questionnaire: relationship with brain structure, cognitive performance and self-reported depressive symptoms in a 25-year retrospective cohort study
(2020-07)
Subjective cognitive complaints are common but it is unclear whether they indicate an underlying pathological process or reflect affective symptoms.
Method:800 community-dwelling older adults were drawn from the Whitehall ...