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Subthalamic nucleus activity dynamics and limb movement prediction in Parkinson’s disease
(2020-02)
Whilst exaggerated bursts of beta frequency band oscillatory synchronization in the subthalamic nucleus have been associated with motor impairment in Parkinson’s disease, a plausible mechanism linking the two phenomena has ...
Examination of the neural basis of psychotic-like experiences in adolescence during processing of emotional faces
(2020-03)
Contemporary theories propose that dysregulation of emotional perception is involved in the aetiology of psychosis. 298 healthy adolescents were assessed at age 14- and 19-years using fMRI while performing a facial emotion ...
Methotrexate and relative risk of dementia amongst patients with rheumatoid arthritis: a multi-national multi-database case-control study
(2020-04)
Background
Inflammatory processes have been shown to play a role in dementia. To understand this role, we selected two anti-inflammatory drugs (methotrexate and sulfasalazine) to study their association with dementia ...
Subjective cognitive complaints given in questionnaire: relationship with brain structure, cognitive performance and self-reported depressive symptoms in a 25-year retrospective cohort study
(2020-07)
Subjective cognitive complaints are common but it is unclear whether they indicate an underlying pathological process or reflect affective symptoms.
Method:800 community-dwelling older adults were drawn from the Whitehall ...
Prevalence, predictors, and prognosis of symptomatic intracranial stenosis in patients with transient ischaemic attack or minor stroke: a population-based cohort study
(2020-05)
Symptomatic intracranial stenosis was perceived to convey a high risk of recurrent stroke, but two previous trials (SAMMPRIS and VISSIT) did not show superiority of intracranial stenosis stenting over intensive medical ...
What we learn about bipolar disorder from large-scaleneuroimaging: Findings and future directions from theENIGMA Bipolar Disorder Working Group
(2020-06)
MRI-derived brain measures offer a link between genes, the environment and behav-ior and have been widely studied in bipolar disorder (BD). However, many neuroimag-ing studies of BD have been underpowered, leading to varied ...
Web-Based and mHealth Technologies to Support Self-Management in People Living With Type 2 Diabetes: Validation of the Diabetes Self-Management and Technology Questionnaire (DSMT-Q)
(2020-07)
Background: A growing number of web-based and mobile health (mHealth) technologies have been developed to support type 2 diabetes self-management. Little is known about individuals’ experiences with these technologies and ...
Patterns in Weight and Physical Activity Tracking Data Preceding a Stop in Weight Monitoring: Observational Analysis
(2020-03)
Background: Self-regulation for weight loss requires regular self-monitoring of weight, but the frequency of weight tracking commonly declines over time.
Objective: This study aimed to investigate whether it is a decline ...
Factors associated with fatigue in CNS inflammatory diseases with AQP4 and MOG antibodies
(2020-02)
Objective: Fatigue is a common and disabling symptom amongst people withmultiple sclerosis, however it has not been compared across the central nervoussystem (CNS) inflammatory diseases associated with aquaporin-4 (AQP4) ...
Dissociating Spatial Attention from Neglect Dyslexia: a Single Case Study
(2020-06)
Word-centred neglect dyslexia is generally thought to be caused by a visuospatial neglect-like attentional deficit which impacts orientation-canonical representations of visual stimuli. However, the relationship between ...