Browsing Conditions by Title
Now showing items 637-656 of 698
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Treating Social Anxiety Disorder Remotely with Cognitive Therapy
(2020-07)Remote delivery of evidence-based psychological therapies via video conference has become particularly relevant following the COVID-19 pandemic, and is likely to be an on-going method of treatment delivery post-COVID. ... -
Treatment for depression comorbid with dementia
(2019-11)Depression is a common comorbidity in dementia. Randomised controlled studies of antidepressants do not show a significant improvement in depressive symptoms in patients with comorbid dementia and are known to lead to an ... -
Treatment of Inappropriate Sexual Behavior in Dementia
(2016-08)Inappropriate sexual behavior (ISB) is a relatively common and potentially disruptive form of behavior in people with dementia. It can cause considerable distress and put placements and people at risk. Yet it is poorly ... -
Treatment Outcomes With Licensed and Unlicensed Stimulant Doses for Adults With Attention-Deficit/Hyperactivity Disorder A Systematic Review and Meta-Analysis
(2023-10)Importance Stimulants (methylphenidate and amphetamines) are often prescribed at unlicensed doses for adults with attention-deficit/hyperactivity disorder (ADHD). Whether dose escalation beyond US Food and Drug Administration ... -
Treatment-resistant depression: therapeutic options when first-line treatments fail
(2021-12)The Cochrane review by Davies et al aimed to address the lack of clarity on the risks and benefits of switching and augmentation strategies in the pharmacological treatment of treatment-resistant depression in adults who ... -
Trends in antidepressant prescriptions in children and young people in England, 1998–2017: protocol of a cohort study using linked primary care and secondary care datasets
(2019-06)Introduction: Increasing numbers of children and young people (CYP) are receiving prescriptions for antidepressants. This is the protocol of a study aiming to describe the trends and variation in antidepressant prescriptions ... -
Typologies for Restructuring Relationships in Cancer Survivorship
(2017-07)Background: Cancer survivors with good social support are generally more motivated to undertake self-management behaviors and make lifestyle changes. However, the impact of changes in social support over time, from ... -
Ultra-processed foods and binge eating: A retrospective observational study
(2021-04)There is increasing evidence of the impact of ultra-processed foods on multiple metabolic and neurobiological pathways, including those involved in eating behaviors, both in animals and in humans. In this study we aimed ... -
Ultradian hydrocortisone replacement alters neuronal processing, emotional ambiguity, affect and fatigue in adrenal insufficiency: The PULSES trial
(2023-10)Background: Primary adrenal insufficiency (PAI) mortality and morbidity remain unacceptably high, possibly arising as glucocorticoid replacement does not replicate natural physiology. A pulsatile subcutaneous pump can ... -
Understanding agoraphobic avoidance: the development of the Oxford Cognitions and Defences Questionnaire (O-CDQ)
(2022-02)Many patients with mental health disorders become increasingly isolated at home due to anxiety about going outside. A cognitive perspective on this difficulty is that threat cognitions lead to the safety-seeking behavioural ... -
Understanding and working with suicide risk
(2015-07)Key learning points: Understanding risk factors associated with suicide; Considering a framework for understanding suicide; How to assess and manage suicide risk -
Understanding clinical decision-making in mesothelioma care: a mixed methods study
(2022-07)Malignant pleural mesothelioma is a rare, incurable cancer arising from previous asbestos exposure; patients have a poor prognosis, with a median survival rate of 8–14 months. Variation in mesothelioma clinical decision-making ... -
Understanding young peoples’ and family members’ views of treatment for first episode psychosis in a randomised controlled trial (MAPS)
(2020-07)Background;There is limited evidence to inform treatment decision-making in adolescents experiencing first episode psychosis (FEP). In the MAPS trial (Managing Adolescent first Episode Psychosis: a feasibility Study), ... -
Understanding, treating, and renaming grandiosedelusions: A qualitative study
(2019-11)Background.Grandiose delusions are arguably the most neglected psychotic experience in research. Objectives.We aimed to discover from patients: whether grandiose delusions have harmful consequences; the psychological ... -
Unraveling Mechanisms of Patient-Specific NRXN1 Mutations in Neuropsychiatric Diseases Using Human Induced Pluripotent Stem Cells
(2020-03)Rare heterozygous deletions in the neurexin 1 (NRXN1) gene robustly increase an individual's risk of developing neurological and psychiatric disorders. However, the molecular bases by which different mutations result in ... -
Unravelling the complex interactions between self-awareness, cognitive change, and mood at 6-months post-stroke using the Y-shaped model
(2022-02)We investigated the relationships between cognitive change following stroke, awareness of cognitive impairments, and mood to further understanding of change processes influencing psychological outcomes post-stroke ... -
Untreatable or unable to treat? Creating more effective and accessible treatment for long-standing and severe eating disorders
(2023-02)The evidence base for the treatment of severe eating disorders is limited. In addition to improving access to early intervention, there is a need to develop more effective treatments for complex presentations of eating ... -
Use and risk of side effects of antiresorptive medication in people with intellectual disabilities [version 1; peer review: awaiting peer review]
(2022-12)Background: Recent studies show that adults with intellectual disabilities (ID) have high incidence of major osteoporotic fracture, especially hip fracture. In those ≥ 50 years, women and men with ID have an approximately ... -
The use of Fox’s glacier mints to treat ibs-type symptoms in patients with anorexia nervosa in an adult specialist eating disorder unit
(2021-03)Background: Patients with Anorexia Nervosa (AN) often experience Irritable Bowel Syndrome (IBS) type symptoms, including bloating, abdominal pain and acid reflux.(1) Pepper mint oil is used to treat IBS symptoms, due to ... -
The use of Intensive Interaction within a Positive Behavioural Support framework
(2021-01)Positive Behavioural Support (PBS) provides an overarching framework for supporting quality‐of‐life improvements for people who use challenging behaviour. Rapport, or the lack of it, is well understood as a setting factor ...