Conditions: Recent submissions
Now showing items 621-640 of 698
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Patient experience of home and waiting room blood pressure measurement: a qualitative study of patients with recently diagnosed hypertension
(2018-12)Background Out-of-office blood pressure (BP) measurement is advocated to confirm hypertension diagnosis. However, little is known about how primary care patients view and use such measurement. Aim To investigate patient ... -
Defining the relationship between arm and leg blood pressure readings: a systematic review and meta-analysis
(2019-04)Objectives: To define the relationship between arm and leg blood pressure (BP) to inform the interpretation of leg BP readings in routine clinical practice where arm readings are not available. Methods: Systematic review ... -
Neuropeptide-Y causes coronary microvascular constriction and is associated with reduced ejection fraction following ST-elevation myocardial infarction
(2019-03)Aims The co-transmitter neuropeptide-Y (NPY) is released during high sympathetic drive, including ST-elevation myocardial infarction (STEMI), and can be a potent vasoconstrictor. We hypothesized that myocardial NPY levels ... -
Differential effects of poor recall and memory disjointedness on trauma symptoms
(2018)Clinical theories of PTSD suggest that trauma memories are disorganised. The present study examined how trauma film exposure affects two aspects of memory disorganisation, poor memory recall and memory disjointedness, and ... -
Experiences of Reframing during Self-Directed Weight Loss and Weight Loss Maintenance: Systematic Review of Qualitative Studies
(2018-06)Background: Reframing means changing the way that a person thinks or feels about a weight loss attempt or weight loss maintenance to enhance its experience or facilitate its success. Although participants have described ... -
Assessing Fluid Resuscitation in Adults with Sepsis Who Are Not Mechanically Ventilated: a Systematic Review of Diagnostic Test Accuracy Studies
(2019-05)BACKGROUND: Fluid resuscitation is a widely used intervention that is mandated in the management of sepsis. While its use can be life-saving, its overuse is associated with harm. Despite this, the best means of assessing ... -
Implementation of the back skills training programme
(2018-02)Purpose of study; To evaluate implementation of the Back Skills Training (BeST) programme in clinical practice within the National Health Service (NHS). Background: The BeST programme is a group Cognitive Behavioural ... -
Conceptual Framework for an Episode of Rehabilitative Care After Surgical Repair of Hip Fracture
(2019-03)Researchers face a challenge when evaluating the effectiveness of rehabilitation after a surgical procedure for hip fracture. Reported outcomes of rehabilitation will vary depending on the end point of the episode of care. ... -
Clinician-targeted interventions to improve advance care planning in heart failure: a systematic review and meta-analysis
(2019-05)Objective Advance care planning (ACP) is widely advocated to contribute to better outcomes for patients suffering from heart failure. But clinicians appear hesitant to engage with ACP. Our aim was to identify interventions ... -
Effectiveness and Acceptability of Cognitive Behavior Therapy Delivery Formats in Adults With Depression A Network Meta-analysis
(2019-04)Importance Cognitive behavior therapy (CBT) has been shown to be effective in the treatment of acute depression. However, whether CBT can be effectively delivered in individual, group, telephone-administered, guided ... -
What is the evidence for using bed rest as part of hospital treatment of severe anorexia nervosa?
(2019-04)Bed rest is commonly used on medical and paediatric wards as part of nursing management of the physically compromised patient with severe anorexia nervosa. The aim of this study was to review the evidence base of bed rest ... -
The Functional Consequences of Social Attention for Memory-guided Attention Orienting and Anticipatory Neural Dynamics
(2019-02)Social attention when viewing natural social (compared to non-social) images has functional consequences on contextual memory in healthy human adults. In addition to attention affecting memory performance, strong evidence ... -
Effects of patient suicide on psychiatrists: survey of experiences and support required
(2019-03)Aims and method Death of patients by suicide can have powerful effects on psychiatrists. We report the findings of a survey completed by 174 psychiatrists on the effects of patient suicide on their emotional well-being ... -
The Oxford study of Calcium channel Antagonism, Cognition, Mood instability and Sleep (OxCaMS): study protocol for a randomised controlled, experimental medicine study
(2019-02)Background: The discovery that voltage-gated calcium channel genes such as CACNA1C are part of the aetiology of psychiatric disorders has rekindled interest in the therapeutic potential of L-type calcium channel (LTCC) ... -
Hebephrenia is dead, long live hebephrenia, or why Hecker and Chaslin were on to something
(2019-05-03)Since its first description in 1863, ‘hebephrenia’ has highlighted a group of patients characterised by an early onset of illness, formal thought disorder, bizarre behaviour and incongruent emotional expression. A proportion ... -
The theory-practice gap in wound care: effective ways of embedding your learning into clinical practice
(2020-12)It has been suggested that there are approximately 2.2 million patients in the UK with a chronic wound (Guest et al, 2016). The cost of managing these wounds and associated comorbidities is approximately £5.3 billion (Guest ... -
A Systematic Review of Professionals' Experiences of Discussing Fertility Issues with Adolescents and Young Adults with Cancer
(2019-03-22)impaired fertility is one potential late effect of cancer, with 15% of adolescents and young adults with cancer (AYAC) at a high risk. Guidelines state that fertility advice should be available at diagnosis; however, ... -
Risk assessment scales to predict risk of hospital treated repeat self-harm: A cost-effectiveness modelling analysis
(2019-04-15)Risk scales are used widely for assessing individuals presenting to Emergency Departments (EDs) following self-harm. There is growing evidence that risk scales have limited clinical utility in identifying episodes at highest ... -
Signal variance-based collateral index in DSC perfusion: A novel method to assess leptomeningeal collateralization in acute ischaemic stroke
(2019-02)As a determinant of the progression rate of the ischaemic process in acute large-vessel stroke, the degree of collateralization is a strong predictor of the clinical outcome after reperfusion therapy and may influence ... -
Association of Cannabis Use in Adolescence and Risk of Depression, Anxiety, and Suicidality in Young Adulthood A Systematic Review and Meta-analysis
(2019-02)Cannabis is the most commonly used drug of abuse by adolescents in the world. While the impact of adolescent cannabis use on the development of psychosis has been investigated in depth, little is known about the impact of ...