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Now showing items 61-70 of 151
Integrated Enhanced Cognitive Behavioural (I-CBTE) therapy significantly improves effectiveness of inpatient treatment of anorexia nervosa in real life settings
(2022-01)
Inpatient treatment of anorexia nervosa (AN) often results in poor outcomes. To address this, the Oxford
service has adapted the multistep enhanced cognitive behavioural (CBTE) treatment model, first
developed in Italy, ...
Identification of Substrate-specific Allosteric Fingerprints in Matrix Metalloprotease-1 on Amyloid-beta Peptide Aggregates and Drug Screening With Single Molecule Insights
(2022-02)
Amyloid-beta peptide (Aβ) is the primary component of water-insoluble extracellular plaques, one of the
critical hallmarks of Alzheimer's disease (AD). Matrix metalloproteases (MMPs) are broad-spectrum
proteases with ...
Pharmacological and non-pharmacological interventions for adults with ADHD: protocol for a systematic review and network meta-analysis
(2022-02)
It is unclear how pharmacological and non-pharmacological interventions compare with each other in terms of efficacy and tolerability for core symptoms and additional problems in adults with attention-deficit/hyperactivity ...
Representation and Outcomes of Individuals With Schizophrenia Seen in Everyday Practice Who Are Ineligible for Randomized Clinical Trials
(2022-02)
IMPORTANCE Most evidence about efficacy and safety of antipsychotics in schizophrenia
spectrum disorders relies on randomized clinical trials (RCTs). However, owing to their strict
eligibility criteria, RCTs represent ...
Outcomes of importance to children and young adults with cerebral palsy, their parents and health professionals following lower limb orthopaedic surgery: A qualitative study to inform a Core Outcome Set
(2022-02)
Introduction: Although several outcomes are commonly measured to assess the
effect of surgery for young people with cerebral palsy (CP), these are selected mainly
by health professionals and researchers. Including the ...
The impact of the COVID-19 pandemic on health service utilisation following selfharm: a systematic review
(2022-01)
Background Evidence on the impacts of the pandemic on healthcare presentations for self-harm has accumulated rapidly. However, existing reviews do not include studies published beyond 2020.
Aims To systematically review ...
“It seems impossible that it’s been made so quickly”: a qualitative investigation of concerns about the speed of COVID-19 vaccine development and how these may be overcome
(2022-02)
The speed of COVID-19 vaccine development has been identified as a central concern contributing to
hesitancy in acceptance. We conducted qualitative interviews to gain a greater understanding into these
concerns and to ...
Women’s information needs around urine testing for urinary tract infections: a qualitative study
(2022-02)
Background Urinary tract infection (UTI) is one of the commonest bacterial infections in general practice, with urine testing a frequent feature of its management. Urinary dipsticks are widely used, with urine culture the ...
Risks, roles and responsibilities: Evaluating falls in inpatient mental healthcare settings for older people
(2022-02)
Background
Despite the large number of falls in mental health settings, we know little about what contributes to falls. The main aim of the study is to explore how fall risk, prevention and management is understood and ...
Long COVID rehabilitation: A collaborative approach to managing a new phenomenon
(2022-02)
Purpose: Post COVID Syndrome (Long COVID) is the continuation of symptoms related to a COVID-like-illness after 12 weeks post onset (NICE Guidelines December 2020). Most recent ONS prevalence data (April 2021) predicts ...