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Clinicians’ views of treatment types for first episode psychosis delivered in a randomised controlled trial (MAPS)
(2020-07)
Background
Clinicians’ treatment beliefs could affect the feasibility of delivering different treatments in a randomised controlled trial (RCT). In MAPS (Managing Adolescent first Episode Psychosis: a feasibility Study), ...
Measuring reasoning in paranoia: Development of the Fast and Slow Thinking Questionnaire
(2020-07)
Paranoid thoughts are common across the psychosis continuum. It is well established that reasoning biases (conceived as an overreliance on fast thinking and lack of willingness and/or ability to engage in slow thinking) ...
The Systemic Assessment Clinic, a Novel Method for Assessing Patients in General Adult Psychiatry: Presentation and Preliminary Service Evaluation.
(2020-08)
The traditional model of psychiatric assessment and diagnosis can be criticised as reductive. We developed an innovative model for psychiatric assessment of adult patients referred to our adult mental health team, the ...
Antipsychotic medication versus psychological intervention versus a combination of both in adolescents with first-episode psychosis (MAPS): a multicentre, three-arm, randomised controlled pilot and feasibility study
(2020-07)
Background
Evidence for the effectiveness of treatments in early-onset psychosis is sparse. Current guidance for the treatment of early-onset psychosis is mostly extrapolated from trials in adult populations. The UK ...
The side effect profile of Clozapine in real world data of three large mental hospitals
(2020-01)
Objective: Mining the data contained within Electronic Health Records (EHRs) can potentially generate a greater understanding of medication effects in the real world, complementing what we know from Randomised control ...
Factors associated with the prescribing of high-dose opioids in primary care: a systematic review and meta-analysis
(2020-03)
Background
The risks of harms from opioids increase substantially at high doses, and high-dose prescribing has increased in primary care. However, little is known about what leads to high-dose prescribing, and studies ...
Patterns in Weight and Physical Activity Tracking Data Preceding a Stop in Weight Monitoring: Observational Analysis
(2020-03)
Background: Self-regulation for weight loss requires regular self-monitoring of weight, but the frequency of weight tracking commonly declines over time.
Objective: This study aimed to investigate whether it is a decline ...
Effective psychological treatment for PTSD changes the dynamics of specific large-‐scale brain networks
(2020-01)
Very
little
is
known
about
the
role
of
effective
cognitive
therapy
in
reversing
imbalances
in
brain
activity
after
trauma.
We
hypothesised
that
exaggerated
threat
perception
characteristic
of
p ...
Pharmacological Treatments for Social Anxiety Disorder in Adults: A Systematic Review and Network Meta-Analysis
(2020-02)
Objective: The aim of this paper was to provide a systematic review and update on the pharmacotherapy of social anxiety disorder (SAD), including the efficacy and tolerability of these agents, the ranking of interventions, ...
Five models for child and adolescent data linkage in the UK: a review of existing and proposed methods
(2020-02)
Over the last decade dramatic advances have been made
in both the technology and data available to better
understand the multifactorial influences on child and
adolescent health and development. This paper seeks
to ...