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Prevalence, predictors, and prognosis of symptomatic intracranial stenosis in patients with transient ischaemic attack or minor stroke: a population-based cohort study
(2020-05)
Symptomatic intracranial stenosis was perceived to convey a high risk of recurrent stroke, but two previous trials (SAMMPRIS and VISSIT) did not show superiority of intracranial stenosis stenting over intensive medical ...
Effect of the NMDA receptor partial agonist, d-cycloserine, on emotional processing and autobiographical memory
(2020-04)
Background: Studies suggest that d-cycloserine (DCS) may have antidepressant potential through its interaction with the glycine site of the N-Methyl-D-aspartate receptor (NMDAR); however clinical evidence of DCS’s efficacy ...
How representative are neuroimaging samples? Large-scale evidence for trait anxiety differences between MRI and behaviour-only research participants.
(2020-04)
Over the past three decades, MRI has become a key tool to study how cognitive processes are implemented in the human brain. However, the question of whether participants recruited into MRI studies differ from participants ...
The importance of different frailty domains in a population based sample in England
(2020-01)
Background
The aim was to estimate the prevalence of frailty and relative contribution of physical/balance, nutritive, cognitive and sensory frailty to important adverse health states (falls, physical activity levels, ...
Why do patients with psychosis listen to and believe derogatory and threatening voices? 2 21 reasons given by patients
(2020-05)
Background: Around two thirds of patients with auditory hallucinations experience derogatory
37 and threatening voices (DTVs). Understandably, when these voices are believed then common
38 consequences can be depression, ...
Comparative efficacy and acceptability of antidepressants, psychotherapies, and their combination for acute treatment of children and adolescents with depressive disorder: a systematic review and network meta-analysis
(2020-07)
Depressive disorders are common in children and adolescents. Antidepressants, psychotherapies, and their combination are often used in routine clinical practice; however, available evidence on the comparative efficacy and ...
Advance care planning in patients referred to hospital for acute medical care
(2020-02)
Advance care planning (ACP) is a voluntary process of discussion about future care between an individual and their care provider. ACP is a key focus of national policy as a means to improve patient centered care at the ...
Physical activity in a pandemic: A new treatment target for psychological therapy.
(2020-06)
The COVID-19 pandemic and its management are placing significant new strains onpeople’s well-being, particularly those with pre-existing mental health conditions. Physicalactivity has been shown to improve mental as well ...
Exploring UK doctors’ attitudes towards online patient feedback: Thematic analysis of survey data
(2020-03)
Introduction
Patients are increasingly using online platforms to give feedback about their health-care experiences. Online feedback has been proposed as a way to drive transformative change in the health service through ...