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Now showing items 1-10 of 12
Using Computational Psychiatry to Rule Out the Hidden Causes of Depression
(2017-08)
In an ideal world, our understanding of the causes of psychiatric disorders would progress by testing mechanistic hypotheses in experimental studies, using the results of these studies to identify situations in which the ...
Symptom trajectories in discontinuation trials.
(2017-02)
Many patients with clinical depression, particularly those with recurrent illness, are treated with maintenance antidepressants after an acute-phase response. But how effective is this approach? The effectiveness of ...
Elevated homocysteine and N-methyl-D-aspartate-receptor antibodies as a cause of behavioural and cognitive decline in 22q11.2 deletion syndrome
(2017-12)
A 19-year-old male with 22q11.2 deletion syndrome presented with a 4-year history of cognitive decline and symptoms suggestive of atypical psychosis. Potential for elevated homocysteine and NMDA-receptor antibodies in the ...
The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis
(2017-09-06)
Summary: Background Sleep difficulties might be a contributory causal factor in the occurrence of mental health problems. If
this is true, improving sleep should benefit psychological health. We aimed to determine whether ...
Improving the effectiveness of psychotherapy in two public hospitals in Nairobi
(2017-08)
This paper is the first in a planned series of papers studying the effectiveness of psychotherapy and counselling in Nairobi. It describes a method for checking the effectiveness of psychotherapy and improving service ...
Experiences of remote mood and activity monitoring in bipolar disorder: a qualitative study
(2017-01)
Mobile technology enables high frequency mood monitoring and automated passive collection of date(e.g.actigraphy) from patients more efficiently and less intrusively than has previously been possible. Such techniques are ...
Typologies for Restructuring Relationships in Cancer Survivorship
(2017-07)
Background: Cancer survivors with good social support are generally more
motivated to undertake self-management behaviors and make lifestyle changes.
However, the impact of changes in social support over time, from ...
A web-based clinical decision tool to support treatment decision-making in psychiatry: a pilot focus group study with clinicians, patients and carers
(2017)
Background
Treatment decision tools have been developed in many fields of medicine, including psychiatry, however benefits for patients have not been sustained once the support is withdrawn. We have developed a web-based ...
Psychosocial interventions in stimulant use disorders: a focus on women
(2017-07)
Purpose of review: Stimulant use disorders are significant contributors to the global burden of disease, with a growing impact on women. Psychosocial interventions are the gold standard for treating this condition, but ...
Affective bias as a rational response to the statistics of rewards and punishments
(2017-10)
Affective bias, the tendency to differentially prioritise the processing of negative relative to positive events, is commonly observed in clinical and non-clinical populations. However, why such biases develop is not known. ...