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Plasma glutathione suggests oxidative stress is equally present in early- and late- onset bipolar disorder
(2018-03)
We previously demonstrated oxidative stress in bipolar patients and a
relationship between the age of illness onset and total glutathione, a principal antioxi-
dant. In this study, we sought to replicate these findings ...
Accuracy of risk scales for predicting repeat self-harm and suicide: a multicentre, population-level cohort study using routine clinical data
(2018-04-25)
Background: Risk scales are used widely in the management of patients presenting to hospital following self-harm. However, there is evidence that their diagnostic accuracy in predicting repeat self-harm is limited. Their ...
Predicting treatment response in depression: the role of anterior cingulate cortex
(2018)
Background:
Identification of biomarkers predicting therapeutic outcome to antidepressant treatment is one of the most important tasks in current research because it may transform the lengthy process of finding the right ...
Is Bed Rest Helpful as an Intervention in the Management of Severe Anorexia Nervosa in Hospitals?
(2018-08)
Background: Bed rest has been part of treatment of severe anorexia nervosa in hospitals both in the UK and internationally. It is commonly used on medical and paediatric wards and both the adult and Junior MARSIPAN [1] ...
Does the UK medical education provide doctors with sufficient skills and knowledge to manage patients with eating disorders safely?
(2018-06)
Background: Eating disorders affect 1%–4% of the population and they are associated with an increased rate of mortality and multimorbidity. Following the avoidable deaths of three people the parliamentary ombudsman called ...