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Now showing items 21-30 of 32
Functional organisation for verb generation in children with developmental language disorder
(2020-12)
Developmental language disorder (DLD) is characterised by difficulties in learning one's native language for no apparent reason. These language difficulties occur in 7% of children and are known to limit future academic ...
The Temporal Dynamics of Sleep Disturbance and Psychopathology in Psychosis: A Digital Sampling Study
(2020-12)
Background: Sleep disruption is a common precursor to deterioration and relapse in people living with
psychotic disorders. Understanding the temporal relationship between sleep and psychopathology is important for identifying ...
Deprescribing antihypertensives in patients with multimorbidity
(2020-10)
Deprescribing preventative medications
such as antihypertensives may reduce
adverse events in some older adults,
leading to improved quality of life. The
Optimising Treatment for Mild Systolic
Hypertension in the ...
Vascular disease and multiple sclerosis: a post-mortem study exploring their relationships
(2020-09)
Vascular comorbidities have a deleterious impact on multiple sclerosis clinical outcomes but it is unclear whether this is mediated
by an excess of extracranial vascular disease (i.e. atherosclerosis) and/or of cerebral ...
Will COVID-19 be the coming of age for point-of-care testing?
(2020-09)
BACKGROUND
As countries deal with the COVID-19
pandemic in varying ways, one area
of agreement is the need to test for the
COVID-19 virus in as many people as
possible. Beeching et al have rightly
pointed out that ...
The Impact of COVID-19 on the Cancer Care of Adolescents and Young Adults and Their Well-Being: Results From an Online Survey Conducted in the Early Stages of the Pandemic
(2020-07)
The COVID-19 pandemic is rapidly evolving, and we learn new details every day. Even though the disrup-tions in our daily routines and health care systems pose many challenges, therein lie many ...
Health Outcome Prioritization in Alzheimer's Disease: Understanding the Ethical Landscape.
(2020-07)
BACKGROUND:Dementia has been described as the greatest global health challenge in the 21st century on account of longevity gains increasing its incidence, escalating health and social care pressures. These pressures highlight ...
Short-term memory advantage for brief durations in human APOE ε4 carriers
(2020-06)
The Apolipoprotein-E (APOE) ε4 gene allele, the highest known genetic risk factor for Alzheimer’s disease, has paradoxically been well preserved in the human population. One possible explanation offered by evolutionary ...
The effectiveness of interventions aimed at improving wellbeing and resilience to stress in first responders: A systematic review
(2020-07)
First responders are routinely exposed to traumatic critical incidents, placing them at higher risk for developing stress-related psychopathology and associated health problems than the general population. Interventions ...
Development of a core outcome set for lower limb orthopaedic surgical interventions in ambulant children and young people with cerebral palsy: a study protocol
(2020-03)
Introduction
Musculoskeletal deformities and gait deviations are common features in ambulatory cerebral palsy (CP). Deformity correction through lower limb orthopaedic surgery is the standard form of care aimed at improving ...