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Now showing items 21-25 of 25
Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease A Randomized Clinical Trial
(2019-11)
IMPORTANCE There are no disease-modifying treatments for Alzheimer disease (AD), the
most common cause of dementia. Minocycline is anti-inflammatory, protects against the toxic
effects of β-amyloid in vitro and in animal ...
Impulse control disorders in Parkinson disease and RBD
(2019-10)
Objective
To describe the prevalence, natural history, and risk factors for impulse control behaviors
(ICBs) among people with Parkinson disease (PD), those with REM sleep behavior disorder
(RBD), and controls.
Metho ...
Predicting motor, cognitive & functional impairment in Parkinson’s
(2019-07)
Objective: We recently demonstrated that 998 features derived from a simple 7-minute smartphone test could distinguish between controls, people with Parkinson’s and people with idiopathic Rapid Eye Movement sleep behavior ...
New Approaches in Hypertension Management: a Review of Current and Developing Technologies and Their Potential Impact on Hypertension Care
(2019-06)
Hypertension is a key risk factor for cardiovascular disease. Currently, around a third of people with hypertension are undiagnosed, and of those diagnosed, around half are not taking antihypertensive medications. The World ...
Assessing Fluid Resuscitation in Adults with Sepsis Who Are Not Mechanically Ventilated: a Systematic Review of Diagnostic Test Accuracy Studies
(2019-05)
BACKGROUND: Fluid resuscitation is a widely used intervention
that is mandated in the management of sepsis.
While its use can be life-saving, its overuse is associated
with harm. Despite this, the best means of assessing ...