Search
Now showing items 1-10 of 22
Understanding, treating, and renaming grandiosedelusions: A qualitative study
(2019-11)
Background.Grandiose delusions are arguably the most neglected psychotic experience in research.
Objectives.We aimed to discover from patients: whether grandiose delusions have harmful consequences; the psychological ...
Prevalence of Non-Affective Psychoses in Individuals with Autism Spectrum Disorders: A Systematic Review
(2019-08)
Autism spectrum disorders (ASD) and non-affective psychoses such as schizophrenia are commonly acknowledged as discrete entities. Previous research has revealed evidence of high comorbidity between these conditions, but ...
The effect of a genetic variant at the schizophrenia associated AS3MT/BORCS7 locus on striatal dopamine function: A PET imaging study
(2019)
One of the most statistically significant loci to result from large-scale GWAS of schizophrenia is 10q24.32. However, it is still unclear how this locus is involved in the pathoaetiology of schizophrenia. The hypothesis ...
Hummingbird Study: a study protocol for a multicentre exploratory trial to assess the acceptance and performance of a digital medicine system in adults with schizophrenia, schizoaffective disorder or first-episode psychosis
(2019-06)
Introduction: In patients with schizophrenia, medication adherence is important for relapse prevention, and effective adherence monitoring is essential for treatment planning. A digital medicine system (DMS) has been ...
The side effect profile of Clozapine in real world data of three large mental hospitals
(2020-01)
Objective: Mining the data contained within Electronic Health Records (EHRs) can potentially generate a greater understanding of medication effects in the real world, complementing what we know from Randomised control ...
‘Van Gogh’ syndrome: a term to approach with caution
(2020-06)
If Van Gogh syndrome is
indeed synonymous with NSSI, then
authors would be advised to keep to
the latter term and the clear criteria
provided by DSM-V.
If the literature
continues to suggest that there is a
specific ...
Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis
(2018-01-30)
Preclinical models propose that the onset of psychosis is associated with hippocampal hyperactivity, thought to be driven by
cortical GABAergic interneuron dysfunction and disinhibition of pyramidal neurons. Recent ...
A compassionate imagery intervention for patients with persecutory delusions
(2021-06)
Negative beliefs about the self, including low self-compassion, have been identified as a putative causal factor in the occurrence of paranoia. Therefore, improving self-compassion may be one route to reduce paranoia.
Aims:
To ...
Brain glutamate concentration in men with early psychosis: a magnetic resonance spectroscopy case–control study at 7 T
(2021-06)
Abnormalities in glutamate neurotransmission are linked to psychotic symptoms and cognitive dysfunction in schizophrenia. magnetic resonance spectroscopy (MRS) provides an acceptable means of measuring glutamate in the ...
The impact of Patient and Public Involvement in the SlowMo study: Reflections on peer innovation
(2021-09)
Background: The SlowMo study demonstrated the effects of SlowMo, an eight-session digitally supported reasoning intervention, on paranoia in a large-scale randomized-controlled trial with 362 participants with schizophre ...