Search
Now showing items 1-7 of 7
Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis
(2018-04)
BACKGROUND Major depressive disorder is one of the most common, burdensome, and costly psychiatric disorders worldwide in adults. Pharmacological and non-pharmacological treatments are available; however, because of ...
Effectiveness of maintenance therapy of lithium vs other mood stabilizers in monotherapy and in combinations: A systematic review of evidence from observational studies
(2018-02)
Objectives: For the first time to present a systematic review of observational studies on the efficiency of lithium
monotherapy in comparison with other maintenance mood stabilizers in monotherapy and in combination.
Methods: ...
Network meta-analysis of antidepressants – Authors' reply
(2018-09-22)
Comments on issues raised with Cipriani et al, 'Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis' ...
A signature-based machine learning model for distinguishing bipolar disorder and borderline personality disorder
(2018)
Mobile technologies offer new opportunities for prospective, high resolution monitoring of long-term health
conditions. The opportunities seem of particular promise in psychiatry where diagnoses often rely on retrospective
and ...
Antidepressants might work for people with major depression: where do we go from here? (Comment)
(2018-06)
The publication of our updated network meta-analysis about antidepressants for the acute treatment of major depression has generated a wide discussion in newspapers, social media, and scientific journals. Based on 522 ...
Comparative economic evaluation of quetiapine plus lamotrigine combination vs quetiapine monotherapy (and folic acid vs placebo) in patients with bipolar depression (cequel)
(2018-12)
Although not licensed for acute bipolar depression, lamotrigine has evidence for efficacy in trials and
its use is recommended in guidelines. So far there had been no prospective health economic evaluation of its
use. ...
Plasma glutathione suggests oxidative stress is equally present in early- and late- onset bipolar disorder
(2018-03)
We previously demonstrated oxidative stress in bipolar patients and a
relationship between the age of illness onset and total glutathione, a principal antioxi-
dant. In this study, we sought to replicate these findings ...