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Now showing items 1-10 of 22
Measuring dissociation across adolescence and adulthood: Developing the short-form Cernis Felt Sense of Anomaly scale (CEFSA-14)
(2023-05)
Dissociation may be important across many mental health disorders, but has been variously
conceptualised and measured. We introduced a conceptualisation of a common type of dissociative
experience, ‘felt sense of anomaly’ ...
Neuroimaging glutamatergic mechanisms differentiating antipsychotic treatment-response
(2023-06)
Glutamatergic dysfunction is associated with failure to respond to antipsychotic medication in individuals with schizophrenia. Our objective was to combine neurochemical and functional brain imaging methods to investigate ...
Development and initial evaluation of a behavioural intervention to support weight management for people with serious mental illness: an uncontrolled feasibility and acceptability study
(2023-03)
The rates of obesity and associated health problems are higher in people with serious mental illness (SMI), such as schizophrenia and bipolar disorder, than the general population. A primary care referral to a behavioural ...
Hippocampal Glutamate, Resting Perfusion and the Effects of Cannabidiol in Psychosis Risk
(2023-03)
Background: Preclinical and human data suggest that the onset of psychosis involves
hippocampal glutamatergic dysfunction, driving hyperactivity/hyperperfusion in a
hippocampal-midbrain-striatal circuit. Whether glutamatergic ...
Paediatric traumatic brain injury as a risk factor for psychosis and psychotic symptoms: a systematic review and meta-analysis
(2023-02)
Psychosis is one of the most disabling psychiatric disorders. Paediatric traumatic brain injury (pTBI) has been cited as a developmental risk factor for psychosis, however this association has never been assessed ...
Identifying individuals at risk of developing psychosis: A systematic review of the literature in primary care services
(2023-01)
Psychosis and related disorders are a major public health issue. Early identification and prevention for those at high risk (at-risk-mental-state, ARMS) is important. General practitioners (GPs) are often the first point ...
The relationship between striatal dopamine and anterior cingulate glutamate in first episode psychosis changes with antipsychotic treatment
(2023-05)
The neuromodulator dopamine and excitatory neurotransmitter glutamate have both been implicated in the pathogenesis of psychosis, and dopamine antagonists remain the predominant treatment for psychotic disorders. To date ...
Shared and separate patterns in brain morphometry across transdiagnostic dimensions
(2023-01)
Determining similarities and differences in brain structure across psychiatric disorders is important to determine if psychiatric taxonomy is reflected in distinct brain structural changes. As previous neuroimaging ...
Preferred treatment outcomes in psychological therapy for voices: a comparison of staff and service-user perspectives
(2023-07)
As access to psychological therapy for voice-hearing continues to increase, it is important to understand what treatment outcomes may be particularly valued by those who coordinate, administer, and engage with such ...
Cognitive Behavioural Therapy for Psychosis
(2023-04)
Cognitive behavioural therapy for psychosis (CBTp) is an evidence-based and flexible therapeutic approach to support clients to meet their goals. The appraisal of anomalous experiences, such as voice hearing, is given a ...