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Neural effects of a single dose of fluoxetine on resting-state functional connectivity in adolescent depression
(2020-11)
Fluoxetine is commonly prescribed in adolescent depression, but the neural mechanisms underlying its action remain poorly understood. Here, we used resting-state functional magnetic resonance imaging to investigate the ...
A single dose of fluoxetine reduces neural limbic responses to anger in depressed adolescents
(2019-01-21)
Depression in adolescence is frequently characterised by symptoms of irritability. Fluoxetine is the antidepressant with
the most favourable benefit:risk ratio profile to treat adolescent depression, but the neural ...
Systematic Review and Meta-analysis: Depressive Symptoms and Risky Behaviors Among Adolescents in Low- and Middle-Income Countries
(2021-05)
Several studies conducted in high-income countries have found an association between depressive symptoms and risky behaviors among adolescents. Evidence from low- and middle-income countries (LMICs), where 90% of the world’s ...
Seeing sadness: Comorbid effects of loneliness and depression on emotional face processing
(2021-05)
Background/objective: Loneliness and depression are highly comorbid, and both are associated with social processing deficits. However, there is a paucity of research aimed at differentiating emotional face-processing ...
Acute neural effects of fluoxetine on emotional regulation in depressed adolescents
(2022-05)
Adolescent major depressive disorder (MDD) is associated with disrupted processing of emotional stimuli and difficulties in cognitive reappraisal. Little is known however about how current pharmacotherapies act to modulate ...