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Now showing items 31-40 of 48
Grey matter microstructural differencesin developmental stuttering
(2021-03)
Theoretical accounts of developmental stuttering implicate dysfunctional cortico-striatal-thalamo-cortical motor loops through the putamen, but empirical evidence of these proposed differences is currently limited. ...
Longitudinal Changes in Parkinson’s Disease Symptoms with and Without Rapid Eye Movement Sleep Behavior Disorder: The Oxford Discovery Cohort Study
(2021-08)
Background: Parkinson’s disease (PD) comorbid with rapid eye movement sleep behavior disorder (RBD) may show more severe motor and non motor symptoms, suggesting a distinct PD subtype. Objective: The aim of this study was ...
Suicidal Thoughts in Patients With Cancer and Comorbid Major Depression: Findings From a Depression Screening Program
(2021-09)
Major depression is found in around ten percent of patients attending cancer clinics. One of the symptoms of major depression, defined in the Diagnostic and Statistical Manual of Mental Disorders (DSM), is “thoughts of ...
Viewpoint: digital paediatrics—so close yet so far away
(2021-09)
Technology is driving a revolution in healthcare, but paediatric services have not fully harnessed the potential. Digital health solutions yet to achieve their promise in paediatrics include electronic health records, ...
Characterising the severity of treatment resistance in unipolar and bipolar depression
(2021-10)
Treatment-resistant depression (TRD) is classically defined according to the number of suboptimal antidepressant responses experienced, but multidimensional assessments of TRD are emerging and may confer some advantages. ...
Exploring the public health potential of RED January, a social media campaign supporting physical activity in the community for mental health: A qualitative study
(2021-10)
RED January is an annual social media campaign challenging individuals to be physically active every day during January, and highlighting the potential for improvements in mood and wellbeing. Our aim was to explore elements ...
Exercise versus usual care after non-reconstructive breast cancer surgery (UK PROSPER): multicentre randomised controlled trial and economic evaluation
(2021-11)
Objective To evaluate whether a structured exercise programme improved functional and health related quality of life outcomes compared with usual care for women at high risk of upper limb disability after breast cancer ...
‘Do not attempt cardiopulmonary resuscitation’ (DNACPR)—difficulty in discussions with older medical inpatients and their families: a survey of hospital doctors
(2021-07)
Objectives To determine, for doctors looking after older medical inpatients: (1) how difficult they find discussions about ‘do not attempt cardiopulmonary resuscitation’ (DNACPR); (2) whether difficulty is associated with ...
Delineating between-subject heterogeneity in alpha networks with Spatio-Spectral Eigenmodes
(2021-10)
Between subject variability in the spatial and spectral structure of oscillatory networks can be highly informative but poses a considerable analytic challenge. Here, we describe a data-driven modal decomposition of a ...
Altered network stability in progressive supranuclear palsy
(2021-07)
The clinical syndromes of Progressive Supranuclear Palsy (PSP) may be mediated by abnormal temporal dynamics of brain networks, due to the impact of atrophy, synapse loss and neurotransmitter deficits. We tested the ...