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Multimodal brain-age prediction and cardiovascular risk: The Whitehall II MRI sub-study
(2020-01)
Brain age is becoming a widely applied imaging-based biomarker of neural aging and potential proxy for brain integrity and health. We estimated multimodal and modality-specific brain age in the Whitehall II MRI cohort using ...
Transient spectral events in resting state MEG predict individual task responses
(2020-07)
Even in response to simple tasks such as hand movement, human brain activity shows remarkable inter-subject
variability. Recently, it has been shown that individual spatial variability in fMRI task responses can be ...
Prediction of brain age and cognitive age: quantifying brain and cognitive maintenance in aging
(2020-06)
The concept of brain maintenance refers to the preservation of brain integrity in older age, whilecognitive reserverefers to the capacity to maintain cognition in the presence of neurodegeneration or aging-related brain ...
Associations Between Longitudinal Trajectories of Cognitive and Social Activities and Brain Health in Old Age
(2020-08)
Importance Prior neuroimaging studies have found that late-life participation in cognitive (eg, reading) and social (eg, visiting friends and family) leisure activities are associated with magnetic resonance imaging (MRI) ...
Dissecting Transient Burst Events
(2020-10)
Increasing efforts are being made to understand the role of intermittent, transient, high-power burst events of neural activity. These events have a temporal, spectral, and spatial domain. Here, we argue that considering ...
Challenges and future directions for representations of functional brain organization
(2020-10)
A key principle of brain organization is the functional integration of brain regions into interconnected networks. Functional MRI
scans acquired at rest offer insights into functional integration via patterns of coherent ...
Dopaminergic modulation of regional cerebral blood flow: An arterial spin labelling study of genetic and pharmacological manipulation of COMT activity
(2021-07)
Dopamine has direct and complex vasoactive effects on cerebral circulation. Catechol-O-methyltransferase (COMT) regulates cortical dopamine, and its activity can be influenced both genetically and pharmacologically. COMT ...
EMD: Empirical Mode Decomposition and Hilbert-Huang Spectral Analyses in Python
(2021-03)
The Empirical Mode Decomposition (EMD) package contains Python (>=3.5) functions for
analysis of non-linear and non-stationary oscillatory time series. EMD implements a family of
sifting algorithms, instantaneous frequency ...
Study Protocol: The Heart and Brain Study
(2021-03)
Background: It is well-established that what is good for the heart is good for the brain. Vascular factors such as hypertension, diabetes, and high cholesterol, and genetic factors such as the apolipoprotein E4 allele ...
Replay bursts in humans coincide with activation of the default mode and parietal alpha networks
(2020-12)
Replay in humans coincides with activity in specific resting brain networks
Clusters of heightened default mode and alpha activity are linked to replay bursts
These networks are characterized by highly synchronized ...