Now showing items 17-36 of 36
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Functional biases in attentional templates from associative memory
(2020-12)In everyday life, attentional templates—which facilitate the perception of task-relevant sensory inputs—are often based on associations in long-term memory. We ask whether templates retrieved from memory are necessarily ... -
Generalizing Brain Decoding Across Subjects with Deep Learning
(2022-05)Decoding experimental variables from brain imaging data is gaining popularity, with applications in brain-computer interfaces and the study of neural representations. Decoding is typically subject-specific and does not ... -
Hierarchical modelling of functional brain networks in population and individuals from big fMRI data
(2021-02)A major goal of large-scale brain imaging datasets is to provide resources for investigating heterogeneous populations. Characterisation of functional brain networks for individual subjects from these datasets will have an ... -
Individual variation in brain microstructural-cognition relationships in aging
(2021-02)While all individuals are susceptible to age-related cognitive decline, significant inter- and intra-individual variability exists. However, the sources of this variation remain poorly understood. Here, we examined the ... -
Introducing the tablet-based Oxford Cognitive Screen-Plus (OCS-Plus) as an assessment tool for subtle cognitive impairments
(2021-04)Here, we present the Oxford Cognitive Screen-Plus, a computerised tablet-based screen designed to briefly assess domain-general cognition and provide more fine-grained measures of memory and executive function. The OCS-Plus ... -
Long read sequencing reveals novel isoforms and insights into splicing regulation during cell state changes
(2021-04)Alternative splicing (AS) is a key mechanism underlying cellular differentiation and a driver of complexity in mammalian neuronal tissues. However, understanding of which isoforms are differentially used or expressed and ... -
Looking ahead in working memory to guide sequential behaviour
(2021-06)Working memory can maintain multiple sensory representations to serve unfolding sequential behaviour, such as while making tea or planning a route. How the human mind juggles internal representations as they become relevant ... -
A macroscopic link between interhemispheric tract myelination and cortico-cortical interactions during action reprogramming
(2021-12)Myelination has been increasingly implicated in the function and dysfunction of the adult human brain. Although it is known that axon myelination shapes axon physiology in animal models, it is unclear whether a similar ... -
Multimodal brain-age prediction and cardiovascular risk: The Whitehall II MRI sub-study
(2020-01)Brain age is becoming a widely applied imaging-based biomarker of neural aging and potential proxy for brain integrity and health. We estimated multimodal and modality-specific brain age in the Whitehall II MRI cohort using ... -
Neuroenhancements in the Military: A Mixed-Method Pilot Study on Attitudes of Staff Officers to Ethics and Rules
(2022-02)Utilising science and technology to maximize human performance is often an essential feature of military activity. This can often be focused on mission success rather than just the welfare of the individuals involved. This ... -
One thing leads to another: anticipating visual object identity based on associative-memory template
(2020-04)Probabilistic associations between stimuli afford memory templates that guide perception through pro-active anticipatory mechanisms. A great deal of work has examined the behavioural consequences and human electrophysiological ... -
Output planning at the input stage in visual working memory
(2021-03)Working memory serves as the buffer between past sensations and future behavior, making it vital to understand not only how we encode and retain sensory information in memory but also how we plan for its upcoming use. We ... -
Prediction of brain age and cognitive age: quantifying brain and cognitive maintenance in aging
(2020-06)The concept of brain maintenance refers to the preservation of brain integrity in older age, whilecognitive reserverefers to the capacity to maintain cognition in the presence of neurodegeneration or aging-related brain ... -
The relationship between frequency content and representational dynamics in the decoding of neurophysiological data
(2022-02)Decoding of high temporal resolution, stimulus-evoked neurophysiological data is increasingly used to test theories about how the brain processes information. However, a fundamental relationship between the frequency ... -
Replay bursts in humans coincide with activation of the default mode and parietal alpha networks
(2020-12)Replay in humans coincides with activity in specific resting brain networks Clusters of heightened default mode and alpha activity are linked to replay bursts These networks are characterized by highly synchronized ... -
Right Lateralized Brain Reserve Offsets Age-Related Deficits in Ignoring Distraction
(2020-09)Age-related deterioration of attention decreases the ability to stay focused on the task at hand due to less efficient selection of relevant information and increased distractibility in the face of irrelevant, but salient ... -
Study Protocol: The Heart and Brain Study
(2021-03)Background: It is well-established that what is good for the heart is good for the brain. Vascular factors such as hypertension, diabetes, and high cholesterol, and genetic factors such as the apolipoprotein E4 allele ... -
Synchronisation of Neural Oscillations and Cross-modal Influences
(2020-04)At any given moment, we receive multiple signals from our different senses. Prior research has shown that signals in one sensory modality can influence neural activity and behavioural performance associated with another ... -
Temporal Expectations Prepare Visual Working Memory for Behavior
(2020-09)Working memory enables us to retain past sensations in service of anticipated task demands. How we prepare for anticipated task demands during working memory retention remains poorly understood. Here, we focused on the ... -
Transient spectral events in resting state MEG predict individual task responses
(2020-07)Even in response to simple tasks such as hand movement, human brain activity shows remarkable inter-subject variability. Recently, it has been shown that individual spatial variability in fMRI task responses can be ...
