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Real-world effect of antidepressants for depressive disorder in primary care: protocol of a population-based cohort study
(2020-06)
Introduction Clinical guidelines recommend antidepressants as the first line of treatment for adults with moderate-to-severe depression. Randomised trials provide the best evidence on the comparative effectiveness of ...
Natural language processing for structuring clinical text data on depression using UK-CRIS
(2020-02)
Background Utilisation of routinely collected electronic health records from secondary care offers unprecedented possibilities for medical science research but can also present difficulties. One key issue is that medical ...
Predicting treatment effects in unipolar depression: A meta-review
(2020-08)
There is increasing interest in clinical prediction models in psychiatry, which focus on developing multivariate algorithms to guide personalized diagnostic or management decisions. The main target of these models is the ...
Identifying outcomes for depression that matter to patients, informal caregivers, and health-care professionals: qualitative content analysis of a large international online survey
(2020-07)
Many clinical trials have assessed treatments for depressive disorders and bipolar depression. However, whether, and which, assessed outcome domains really matter to patients, informal caregivers, and health-care professionals ...
Associations between statin use and suicidality, depression, anxiety, and seizures: a Swedish total-population cohort study
(2020-11)
Background
Statins have shown both protective and adverse associations with neuropsychiatric outcomes. We aimed to examine the possible associations between statins and suicidality, depression, anxiety, and seizures.
M ...