Search
Now showing items 1-3 of 3
The Early Youth Engagement in first episode psychosis (EYE-2) study: pragmatic cluster randomised controlled trial of implementation, effectiveness and cost-effectiveness of a team-based motivational engagement intervention to improve engagement
(2021-04)
Background
Early Intervention in Psychosis (EIP) services improve health outcomes for young people with psychosis in the medium–long term, but 25% of young people disengage in the first 12 months with costs to their mental ...
Brain glutamate concentration in men with early psychosis: a magnetic resonance spectroscopy case–control study at 7 T
(2021-06)
Abnormalities in glutamate neurotransmission are linked to psychotic symptoms and cognitive dysfunction in schizophrenia. magnetic resonance spectroscopy (MRS) provides an acceptable means of measuring glutamate in the ...
Endocannabinoid system mediates the association between gut-microbial diversity and anhedonia/amotivation in a general population cohort
(2021-05)
Anhedonia and amotivation are debilitating symptoms and represent unmet therapeutic needs in a range of clinical conditions. The gut-microbiome-endocannabinoid axis might represent a potential modifiable target for ...