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Patient fibroblast circadian rhythms predict lithium sensitivity in bipolar disorder
(2020-05)
Bipolar disorder is a chronic neuropsychiatric condition associated with mood instability, where patients present significant sleep and circadian rhythm abnormalities. Currently, the pathophysiology of bipolar disorder ...
Why sleep matters for young people who may get depressed
(2020-04)
Depression and anxiety are negative emotional states familiar to us all through personal experience. Less familiar are severe states of depression, in particular, which can actually shorten the lives of sufferers by over ...
Actigraphic patterns, impulsivity and moodinstability in bipolar disorder, borderlinepersonality disorder and healthy controls.
(2020-01)
Objectives:To differentiate the relation between the structure and timing of rest-activity patterns and symptoms of impulsivity and mood instability in bipolar disorder (BD), borderline personality disorder(BPD) and healthy ...
Mood Homeostasis, Low Mood, and History of Depression in 2 Large Population Samples
(2020-04)
Importance Existing therapeutic options are insufficient to tackle the disease burden of depression, and new treatments are sorely needed. Defining new psychotherapeutic targets is challenging given the paucity of coherent ...
Efficacy of digital cognitive behavioral therapy for moderate to severe symptoms of generalized anxiety disorder: A randomized controlled trial
(2020-07)
Cognitive behavioral therapy (CBT) is an efficacious intervention for generalized anxiety disorder (GAD). Digital CBT may provide a scalable means of delivering CBT at a population level. We investigated the efficacy of a ...