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Value of monitoring negative emotional bias in primary care in England for personalised antidepressant treatment: a modelling study
(2019-11)
Depressed patients often focus on negative life events. Effective antidepressant therapy reverses this negative emotional bias (NEB) within 1 week. Clinical therapeutic effect usually requires 4–6 weeks. The value of ...
Smoking and the risk for bipolar disorder: evidence from a bidirectional Mendelian randomisation study
(2019-09)
Background:There is increasing evidence that smoking is a risk factor for severe mental illness, including bipolar disorder. Conversely, patients with bipolar disorder might smoke more (often) as a result of the psychiatric ...
Predicting Treatment Response to Antidepressant Medication Using Early Changes in Emotional Processing.
(2019-01)
Antidepressants must be taken for weeks before response can be assessed with many patients not responding to the first medication prescribed. This often results in long delays before effective treatment is started. ...
Investigation of the impact of total sleep deprivation at home on the number of intrusive memories to an analogue trauma
(2019-02)
Sleep enhances the consolidation of memory; however, this property of sleep may be detrimental in situations where memories of an event can lead to psychopathology, such as following a traumatic event. Intrusive memories ...