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Subjective cognitive complaints given in questionnaire: relationship with brain structure, cognitive performance and self-reported depressive symptoms in a 25-year retrospective cohort study
(2020-07)
Subjective cognitive complaints are common but it is unclear whether they indicate an underlying pathological process or reflect affective symptoms.
Method:800 community-dwelling older adults were drawn from the Whitehall ...
Ketamine treatment for depression: qualitative study exploring patient views
(2021-01)
Ketamine is a new and promising treatment for depression but comes with challenges to implement because of its potential for abuse.
Aims
We sought the views of patients to inform policy and practical decisions about ...
Multi-scale neural signatures of major depressive, anxiety, and stress-related disorders
(2021-07)
The extent of shared and distinct neural mechanisms underlying major depressive disorder (MDD), anxiety and stress-related disorders is still unclear. We compared the neural signatures of these disorders in 5,405 UK Biobank ...
The effectiveness of interventions aimed at improving wellbeing and resilience to stress in first responders: A systematic review
(2020-07)
First responders are routinely exposed to traumatic critical incidents, placing them at higher risk for developing stress-related psychopathology and associated health problems than the general population. Interventions ...
Suicidal Thoughts in Patients With Cancer and Comorbid Major Depression: Findings From a Depression Screening Program
(2021-09)
Major depression is found in around ten percent of patients attending cancer clinics. One of the symptoms of major depression, defined in the Diagnostic and Statistical Manual of Mental Disorders (DSM), is “thoughts of ...
Characterising the severity of treatment resistance in unipolar and bipolar depression
(2021-10)
Treatment-resistant depression (TRD) is classically defined according to the number of suboptimal antidepressant responses experienced, but multidimensional assessments of TRD are emerging and may confer some advantages. ...