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Identification of Substrate-specific Allosteric Fingerprints in Matrix Metalloprotease-1 on Amyloid-beta Peptide Aggregates and Drug Screening With Single Molecule Insights
(2022-02)
Amyloid-beta peptide (Aβ) is the primary component of water-insoluble extracellular plaques, one of the
critical hallmarks of Alzheimer's disease (AD). Matrix metalloproteases (MMPs) are broad-spectrum
proteases with ...
Women’s information needs around urine testing for urinary tract infections: a qualitative study
(2022-02)
Background Urinary tract infection (UTI) is one of the commonest bacterial infections in general practice, with urine testing a frequent feature of its management. Urinary dipsticks are widely used, with urine culture the ...