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Multifactorial interventions for preventing falls in older people living in the community: a systematic review and meta-analysis of 41 trials and almost 20 000 participants
(2019-08)
Objective To assess the longer term effects of multifactorial interventions for preventing falls in older people living in the community, and to explore whether prespecific trial-level characteristics are associated with ...
Association of midlife stroke risk with structural brain integrity and memory performance at older ages: a longitudinal cohort study
(2020-03)
Cardiovascular health in midlife is an established risk factor for cognitive function later in life. Knowing mechanisms of this associationmay allow preventative steps to be taken to preserve brain health and cognitive ...
Deprescribing antihypertensives in patients with multimorbidity
(2020-10)
Deprescribing preventative medications
such as antihypertensives may reduce
adverse events in some older adults,
leading to improved quality of life. The
Optimising Treatment for Mild Systolic
Hypertension in the ...
Better Outcomes for Older people with Spinal Trouble (BOOST) Trial: a randomised controlled trial of a combined physical and psychological intervention for older adults with neurogenic claudication, a protocol
(2018-11)
Introduction: Neurogenic claudication due to spinal stenosis is common in older adults. The effectiveness of conservative interventions is not known. The aim of the study is to estimate the clinical and cost-effectiveness ...
Connections Between Insomnia and Cognitive Aging.
(2019-06)
Insomnia is a common sleep disorder among older adults, and a risk factor for poor physical and mental health. However, the relationship between insomnia and cognitive health is not well understood. Here, we review ...
Treatment of Inappropriate Sexual Behavior in Dementia
(2016-08)
Inappropriate sexual behavior (ISB) is a relatively common and potentially disruptive form of behavior in people with dementia. It can cause considerable distress and put placements and people at risk. Yet it is poorly ...
Blood pressure changes following antihypertensive medication reduction, by drug class and dose chosen for withdrawal: Exploratory analysis of data from the OPTiMISE trial
(2021-02)
Aims: Deprescribing of antihypertensive drugs is recommended for some older patients with
polypharmacy, but there is little evidence to inform which drug (or dose) should be
withdrawn. This study used data from the ...
Negative bias in interpretation and facial expression recognition in late life depression: A case control study.
(2021-04)
While cognitive bias in younger adults with depression has been extensively researched, there have been relatively few investigations of the presence of cognitive bias in late life depression (LLD). This exploratory study ...
The Convergent Validity of the electronic Frailty Index (eFI) with the Clinical Frailty Scale (CFS)
(2020-11)
Background: Different scales are being used to measure frailty. This study examined the convergent validity of the electronic Frailty Index (eFI) with the Clinical Frailty Scale (CFS). Method: The cross-sectional study ...
Risks, roles and responsibilities: Evaluating falls in inpatient mental healthcare settings for older people
(2022-02)
Background
Despite the large number of falls in mental health settings, we know little about what contributes to falls. The main aim of the study is to explore how fall risk, prevention and management is understood and ...