Browsing Conditions by Author "Macdonald, Orla"
Now showing items 1-3 of 3
-
COVID-19 and substance use disorders: a review of international guidelines for frontline healthcare workers of addiction services
Ostinelli, Edoardo; Smith, Katharine A; Zangani, Caroline; Macdonald, Orla; Cipriani, Andrea (2022-03)People with substance use disorders may be at a greater risk of contracting COVID-19 infection and developing medical complications. Several institutional and governmental health agencies across the world developed ad hoc ... -
Impact of the COVID-19 Pandemic on the Global Delivery of Mental Health Services and Telemental Health: Systematic Review
Macdonald, Orla; Reid, Katherine; Bale, Robert; Hawton, Keith; Cipriani, Andrea (2022-08)The COVID-19 pandemic required mental health services around the world to adapt quickly to the new restrictions and regulations put in place to reduce the risk of transmission. As face-to-face contact became difficult, ... -
A phase 2a randomised, double-blind, placebo-controlled, parallel-group, add-on clinical trial of ebselen (SPI-1005) as a novel treatment for mania or hypomania.
Sharpley, Ann L; Williams, Clare; Holder, Adele A; Godlewska, Beata R; Macdonald, Orla; Cowen, Philip J (2020-09)Rationale Lithium is an effective prophylactic and anti-manic treatment in bipolar disorder; however, its use is declining through perceived poor tolerance and toxicity. Lithium inhibits inositol monophosphatase (IMPase), ...