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dc.contributor.authorBaruch, Nina
dc.date.accessioned2019-10-28T11:49:03Z
dc.date.available2019-10-28T11:49:03Z
dc.date.issued2019-11
dc.identifier.citationNina Baruch, Jennifer Burgess, Manjunadh Pillai, Charlotte Louise Allan. Treatment for depression comorbid with dementia. Evidence Based Mental Health Nov 2019 Vol 22 Iss 4en
dc.identifier.issn1468-960X
dc.identifier.urihttps://oxfordhealth-nhs.archive.knowledgearc.net/handle/123456789/344
dc.description.abstractDepression is a common comorbidity in dementia. Randomised controlled studies of antidepressants do not show a significant improvement in depressive symptoms in patients with comorbid dementia and are known to lead to an increase in side effects. However, there are relatively few studies of depression in dementia, and drawing firm conclusions about the use of antidepressants is limited by the amount of data available. Furthermore, it is unclear whether data can be extrapolated from similar populations (eg, those with late-life depression) to inform pharmacotherapy in this patient group. Given the lack of effectiveness and risk of side effects associated with pharmacological treatments, psychological interventions may offer important therapeutic benefits. There is evidence for the effectiveness of individual psychological therapy, and further research will establish which psychological approach is the most effective. Some studies have shown an improvement in depressive symptoms using structured sleep hygiene programmes, exercise, arts interventions and music therapy. These studies are hampered by small data sets, and the benefits to individuals may not be well captured by standard outcome measures. At present, the best evidence for arts-based approaches is in music therapy. Depression with comorbid dementia responds well to electroconvulsive therapy and this is a useful treatment modality for those with severe or life-threatening depressive symptoms. Alternative neurostimulation techniques such as transcranial magnetic stimulation are not widely used at present and further research is needed before they can be a more widely used treatment modalityen
dc.description.sponsorshipAvailable with an eligible NHS OpenAthens log inen
dc.description.urihttp://dx.doi.org/10.1136/ebmental-2019-300113
dc.language.isoenen
dc.subjectDepressive Disordersen
dc.subjectDementiaen
dc.subjectPsychotherapyen
dc.subjectElectroconvulsive Therapy (ECT)en
dc.subjectMusic Therapyen
dc.titleTreatment for depression comorbid with dementiaen
dc.typeArticleen


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