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Subthalamic nucleus activity dynamics and limb movement prediction in Parkinson’s disease
(2020-02)
Whilst exaggerated bursts of beta frequency band oscillatory synchronization in the subthalamic nucleus have been associated with motor impairment in Parkinson’s disease, a plausible mechanism linking the two phenomena has ...
Factors associated with fatigue in CNS inflammatory diseases with AQP4 and MOG antibodies
(2020-02)
Objective: Fatigue is a common and disabling symptom amongst people withmultiple sclerosis, however it has not been compared across the central nervoussystem (CNS) inflammatory diseases associated with aquaporin-4 (AQP4) ...
The role of pontine lesion location in differentiating multiple sclerosis from vascular risk factor-related small vessel disease
(2020-08)
Background:
Differentiating multiple sclerosis (MS) from vascular risk factor (VRF)-small vessel disease (SVD) can be challenging.
Objective and Methods:
In order to determine whether or not pontine lesion location ...
Vascular disease and multiple sclerosis: a post-mortem study exploring their relationships
(2020-09)
Vascular comorbidities have a deleterious impact on multiple sclerosis clinical outcomes but it is unclear whether this is mediated
by an excess of extracranial vascular disease (i.e. atherosclerosis) and/or of cerebral ...
Outcome domains and measures after lower limb orthopaedic surgery for ambulant children with cerebral palsy: an updated scoping review
(2020-06)
Aim: To determine the reported outcome domains and measures used to assess lower limb orthopaedic surgery of ambulant children and young people with cerebral palsy (CP) and map these outcomes to the International Classification ...
Development of a core outcome set for lower limb orthopaedic surgical interventions in ambulant children and young people with cerebral palsy: a study protocol
(2020-03)
Introduction
Musculoskeletal deformities and gait deviations are common features in ambulatory cerebral palsy (CP). Deformity correction through lower limb orthopaedic surgery is the standard form of care aimed at improving ...