Browsing Depressive Disorders by Author "Scaife, Jessica"

Now showing items 1-2 of 2

    • Catechol-O-methyltransferase activity does not influence emotional processing in men 

      Martens, M A G; Scaife, Jessica; Harmer, Catherine J; Harrison, Paul J; Tunbridge, Elizabeth (2022-04)
      Background: Catechol-O-methyltransferase (COMT) regulates cortical dopaminergic transmission and prefrontal-dependent cognitive function. However, its role in other cognitive processes, including emotional processing, is ...

    • Translating the promise of 5HT4 receptor agonists for the treatment of depression 

      Murphy, Susannah E; De Cates, Angharad N; Gillespie, Amy L; Godlewska, Beata R; Scaife, Jessica; Wright, Lucy C; Cowen, Philip J; Harmer, Catherine J (2020-02)
      Animal experimental studies suggest that 5-HT4 receptor activation holds promise as a novel target for the treatment of depression and cognitive impairment. 5-HT4 receptors are postsynaptic receptors that are located in ...