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Now showing items 61-70 of 201
A Phenomenological Exploration of the Voices Reported by Borderline Personality and Schizophrenia Patients
(2021-06)
Introduction: Over time, there have been different views regarding the verbal auditory hallucinations (VAHs) reported by borderline personality disorder (BPD) and schizophrenia patients. More recently, their similarity has ...
mHealth Interventions for Self-Harm: Scoping Review
(2021-04)
Background: Self-harm is a growing issue with increasing prevalence rates; however, individuals who self-harm do not often
receive treatment. Mobile health (mHealth) interventions are a possible solution to some of the ...
Shielding working-memory representations from temporally predictable external interference
(2021-05)
Protecting working-memory content from distracting external sensory inputs and intervening tasks is a ubiquitous demand in daily life. Here, we ask whether and how temporal expectations about external events can help ...
A continuum hypothesis of psychotomimetic rapid antidepressants
(2021-05)
Ketamine, classical psychedelics and sleep deprivation are associated with rapid effects on depression. Interestingly, these interventions also have common psychotomimetic actions, mirroring aspects of psychosis such as ...
Long read sequencing reveals novel isoforms and insights into splicing regulation during cell state changes
(2021-04)
Alternative splicing (AS) is a key mechanism underlying cellular differentiation and a driver of
complexity in mammalian neuronal tissues. However, understanding of which isoforms are
differentially used or expressed and ...
Effects of SlowMo, a Blended Digital Therapy Targeting Reasoning, on Paranoia Among People With Psychosis A Randomized Clinical Trial
(2021-04)
IMPORTANCE Persistent paranoia is common among patients with psychosis.
Cognitive-behavioral therapy for psychosis can be effective. However, challenges
in engagement and effectiveness remain.
OBJECTIVE To investigate ...
Introducing the tablet-based Oxford Cognitive Screen-Plus (OCS-Plus) as an assessment tool for subtle cognitive impairments
(2021-04)
Here, we present the Oxford Cognitive Screen-Plus, a computerised tablet-based screen designed to briefly assess domain-general cognition and provide more fine-grained measures of memory and executive function. The OCS-Plus ...
Using digital monitoring alongside psychosocial interventions in patients who self-harm
(2021-05)
With more than 200,000 presentations to hospital for self-harm each year in England, there is a clear requirement to reduce self-harm and improve well-being in this population. This service evaluation examined the potential ...
A retrospective examination of care pathways in individuals with treatment-resistant depression
(2021-05)
Individuals with treatment-resistant depression (TRD) experience a high burden of illness. Current guidelines recommend a stepped care approach for treating depression, but the extent to which best-practice care pathways ...
Systematic Review and Meta-analysis: Depressive Symptoms and Risky Behaviors Among Adolescents in Low- and Middle-Income Countries
(2021-05)
Several studies conducted in high-income countries have found an association between depressive symptoms and risky behaviors among adolescents. Evidence from low- and middle-income countries (LMICs), where 90% of the world’s ...